Results 181 to 190 of about 82,686 (281)

Sensor histidine kinase QseC [PDF]

open access: yesScience-Business eXchange, 2008
openaire   +1 more source

Targeting the Spliceosomal Protein USP39 Through Allosteric Ligands and PROTAC‐Induced Degradation

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Proteolysis‐targeting chimeras (PROTACs) enable degradation of proteins previously considered undruggable by harnessing the cellular ubiquitin–proteasome system. In this study, Schäfer et al. identify thiazole‐based small molecules that allosterically bind the zinc finger domain of ubiquitin‐specific protease 39 (USP39), a non‐enzymatic scaffold ...
Daniel Schäfer   +11 more
wiley   +1 more source

Auxin-Producing Pseudomonas Recruited by Root Flavonoids Increases Rice Rhizosheath Formation through the Bacterial Histidine Kinase Under Soil Drying. [PDF]

open access: yesAdv Sci (Weinh)
Xu F   +23 more
europepmc   +1 more source

Human neutrophil defensin-1 binding increases histidine kinase activity of SaeS in <i>Staphylococcus aureus</i>. [PDF]

open access: yesBiochem Biophys Rep
Qi Z   +8 more
europepmc   +1 more source

Structural features discriminating hybrid histidine kinase Rec domains from response regulator homologs. [PDF]

open access: yesNat Commun, 2023
Brüderlin M   +5 more
europepmc   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

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