Results 191 to 200 of about 82,686 (281)

Activation of the <i>Staphylococcus aureus</i> intramembrane sensing histidine kinase SaeS via intramembrane interaction with the bacterially encoded small protein ScrA. [PDF]

mBio
Wittekind MA, Monk IR, Steere RW, Sudnick EG, Holzschu D, Deighan P, Stinear TP, Carroll RK.   +7 more
europepmc   +1 more source

The sensor histidine kinase (SLN1) and acetyl-CoA carboxylase (ACC1) coordinately regulate the response of Neurospora crassa to the springtail Sinella curviseta (Collembola: Entomobryidae) attack. [PDF]

Appl Environ Microbiol, 2023
Sun M, Lu T, Chen P, Wang X, Yang H, Zhou R, Zheng W, Zhao Y.   +7 more
europepmc   +1 more source

Transmembrane Prolines Mediate Signal Sensing and Decoding in Bacillus subtilis DesK Histidine Kinase. Supplemental material.

, 2019
Pilar Fernández, Lucía Porrini, Daniela Albanesi, Luciano A. Abriata, Matteo Dal Peraro, Diego de Mendoza, Marı́a C. Mansilla   +6 more
openalex   +1 more source

The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier [PDF]

, 2002
Andreas Böck, Roy Gross
openalex   +1 more source

Engineering of an Ancestral McbA with Enhanced Domain Mobility Extends Biocatalytic Amide Synthesis Scope

Advanced Synthesis &Catalysis, Volume 368, Issue 2, January 2026.
We show how engineered ancestral amide bond synthetases (ABSs) together with cofactor recycling using a single polyphosphate kinase paves the way for chemoenzymatic synthesis of pharmacophores. The figure illustrates how ancestral ABS has a more flexible C‐terminal domain, which is associated with enhanced catalytic performance and expanded amine scope.
Elisabeth Söderberg, Marianne R. Molenaar, Katarzyna Zaczyk, Magnus Johansson, Martin A. Hayes, Per‐Olof Syrén   +5 more
wiley   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

Atomic insights into the signaling landscape of E. coli PhoQ histidine kinase from molecular dynamics simulations. [PDF]

Sci Rep
Lazaridi S, Yuan J, Lemmin T.
europepmc   +2 more sources

High-level cefiderocol and ceftazidime/avibactam resistance in KPC-producing Klebsiella pneumoniae associated with mutations in KPC and the sensor histidine kinase EnvZ. [PDF]

J Antimicrob Chemother
Findlay J, Bianco G, Boattini M, Nordmann P.   +3 more
europepmc   +1 more source

Four signalling domains in the hybrid histidine protein kinase RodK of Myxococcus xanthus are required for activity [PDF]

, 2006
Anders Aa. Rasmussen, Sigrun Wegener‐Feldbrügge, Steven L. Porter, Judith P. Armitage, Lotte Søgaard‐Andersen   +4 more
openalex   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

Advanced Science, Volume 13, Issue 6, 30 January 2026.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin, Meilian Yao, Xin Xu, Dong Zhang, Lei Xu, Ling Rong, Xiaohang Wang, Yi Duan, Chengkun Chen, Jun Gu, Yao Zhang, Qiang Liu, Qing Ye, Gaoping Cui, Yujun Hao, Xiumei Ma   +15 more
wiley   +1 more source