Results 41 to 50 of about 1,192,564 (261)

NikA/TcsC histidine kinase is involved in conidiation, hyphal morphology, and responses to osmotic stress and antifungal chemicals in Aspergillus fumigatus. [PDF]

open access: yesPLoS ONE, 2013
The fungal high osmolarity glycerol (HOG) pathway is composed of a two-component system (TCS) and Hog1-type mitogen-activated protein kinase (MAPK) cascade.
Daisuke Hagiwara   +7 more
doaj   +1 more source

Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance All living things must sense and react to their environment. Many single-celled organisms do so by using two-component systems, most simply consisting of a sensor histidine kinase and a response regulator.
I. Dikiy   +6 more
semanticscholar   +1 more source

Design, characterization and in vivo functioning of a light-dependent histidine protein kinase in the yeast Saccharomyces cerevisiae

open access: yesAMB Express, 2018
Helical alignment of the α-helical linker of the LOV (light-oxygen-voltage) domain of YtvA from Bacillus subtilis with the α-helical linker of the histidine-protein kinase domain of the Sln1 kinase of the phospho-relay system for osmoregulation of ...
Aleksandra Bury, Klaas J. Hellingwerf
doaj   +1 more source

Regulation of nitric oxide signaling by formation of a distal receptor-ligand complex. [PDF]

open access: yes, 2017
The binding of nitric oxide (NO) to the heme cofactor of heme-nitric oxide/oxygen binding (H-NOX) proteins can lead to the dissociation of the heme-ligating histidine residue and yield a five-coordinate nitrosyl complex, an important step for NO ...
Britt, R David   +5 more
core   +1 more source

Signaling ammonium across membranes through an ammonium sensor histidine kinase

open access: yesNature Communications, 2018
Sensing and uptake of external ammonium is essential for anaerobic ammonium-oxidizing (anammox) bacteria, and is typically the domain of the ubiquitous Amt/Rh ammonium transporters.
Tobias Pflüger   +9 more
semanticscholar   +1 more source

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus

open access: yesNature Communications, 2018
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality.
I. Monk   +20 more
semanticscholar   +1 more source

Transposon and deletion mutagenesis of genes involved in perchlorate reduction in Azospira suillum PS. [PDF]

open access: yes, 2013
UnlabelledAlthough much work on the biochemistry of the key enzymes of bacterial perchlorate reduction, chlorite dismutase, and perchlorate reductase has been published, understanding of the molecular mechanisms of this metabolism has been somewhat ...
Clark, Iain C   +3 more
core   +2 more sources

HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase

open access: yesmBio, 2015
HAMP domains are α-helical coiled coils that often transduce signals from extracytoplasmic sensing domains to cytoplasmic domains. Limited structural information has resulted in hypotheses that specific HAMP helix movement changes downstream enzymatic ...
Susana Matamouros   +2 more
doaj   +1 more source

NM23-H1: a Metastasis-Associated Gene

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2006
The protein product of nm23-H1 gene has activity of nucleoside diphosphate (NDP) kinase, which catalyzes the phosphorylation of nucleoside diphosphates to the corresponding nucleoside triphosphates.
Yi-Torng Tee   +4 more
doaj   +1 more source

Spontaneous and CRISPR/Cas9-induced mutation of the osmosensor histidine kinase of the canola pathogen Leptosphaeria maculans

open access: yesFungal Biology and Biotechnology, 2017
BackgroundThe dicarboximide fungicide iprodione has been used to combat blackleg disease of canola (Brassica napus), caused by the fungus Leptosphaeria maculans.
A. Idnurm   +5 more
semanticscholar   +1 more source

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