Norovirus Binding to Ligands Beyond Histo-Blood Group Antigens [PDF]
Histo-blood group antigens (HBGAs) are commonly accepted as the cellular receptors for human norovirus. However, some human noroviruses have been found not to bind any HBGA ligand, suggesting potential additional co-factors.
Erin A. Almand +3 more
doaj +6 more sources
Norovirus Recognition Sites on Histo-blood Group Antigens [PDF]
Norovirus (NoV) is the major causative agent of acute viral gastroenteritis worldwide. Based on genetic analyses, human NoV strains have been classified into at least three genogroups: genogroup I (GI), GII, and GIV, which contain at least 15, 18, and 1 genotypes, respectively (Kageyama et al., 2004).
Haruko eShirato
doaj +6 more sources
Histo-Blood Group Antigens in Children with Symptomatic Rotavirus Infection [PDF]
Group A rotaviruses are a major cause of acute gastroenteritis in children. The diversity and unequal geographical prevalence of rotavirus genotypes have been linked to histo-blood group antigens (HBGAs) in different human populations.
Raúl Pérez-Ortín +5 more
doaj +6 more sources
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis [PDF]
Noroviruses have been identified as major causative agents of acute nonbacterial gastroenteritis in humans. Histo‐blood group antigens (HBGAs) are thought to play a major role among the host cellular factors influencing norovirus infection.
Tomomi Kimura‐Someya +7 more
doaj +3 more sources
Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens. [PDF]
Rotavirus is the leading agent causing acute gastroenteritis in young children, with the P[8] genotype accounting for more than 80% of infections in humans.
Roberto Gozalbo-Rovira +8 more
doaj +4 more sources
Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens [PDF]
Human norovirus interacts with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. The genogroup II genotype 4 (GII.4) noroviruses are the dominant cluster, evolve every other year, and
Bishal K. Singh +2 more
doaj +6 more sources
Background: Pseudomonas aeruginosa is not a common enteric pathogen. The association between human histo-blood group antigens (HBGAs) and P. aeruginosa enteric infection has not yet been studied.
Chih-Hsien Chuang +5 more
doaj +4 more sources
Human noroviruses' fondness for histo-blood group antigens. [PDF]
ABSTRACT Human noroviruses are the dominant cause of outbreaks of gastroenteritis around the world. Human noroviruses interact with the polymorphic human histo-blood group antigens (HBGAs), and this interaction is thought to be important for infection. Indeed, synthetic HBGAs or HBGA-expressing enteric bacteria were shown to enhance norovirus
Singh BK, Leuthold MM, Hansman GS.
europepmc +5 more sources
Histo-blood group antigens and rotavirus vaccine shedding in Nicaraguan infants. [PDF]
AbstractABO, Lewis and secretor histo-blood group antigens (HBGA) are susceptibility factors for rotavirus in a P-genotype dependent manner and can influence IgA seroconversion rates following rotavirus vaccination. To investigate the association between HBGA phenotypes and rotavirus vaccine shedding fecal samples (n = 304) from a total of 141 infants ...
Bucardo F +6 more
europepmc +6 more sources
Bovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens. [PDF]
ABSTRACT Some viruses within the Caliciviridae family initiate their replication cycle by attachment to cell surface carbohydrate moieties, histo-blood group antigens (HBGAs), and/or terminal sialic acids (SAs).
Cho EH +11 more
europepmc +5 more sources

