Histo-blood group antigens: a common niche for norovirus and rotavirus. [PDF]
Expert Rev Mol Med, 2014 Noroviruses (NoVs) and rotaviruses (RVs), the two most important causes of viral acute gastroenteritis, are found to recognise histo-blood group antigens (HBGAs) as receptors or ligands for attachment. Human HBGAs are highly polymorphic containing ABO, secretor and Lewis antigens.
Tan M, Jiang X.
europepmc +5 more sources
Rotavirus VP8*: phylogeny, host range, and interaction with histo-blood group antigens. [PDF]
J Virol, 2012 ABSTRACT The distal portion of rotavirus (RV) VP4 spike protein (VP8*) is implicated in binding to cellular receptors, thereby facilitating viral attachment and entry. While VP8* of some animal RVs engage sialic acid, human RVs often attach to and enter cells in a sialic acid-independent manner.
Liu Y +8 more
europepmc +5 more sources
The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae [PDF]
Microbiology Spectrum, 2022 Human norovirus (HuNoV) is the major agent for viral gastroenteritis, causing >700 million infections yearly. Fucose-containing carbohydrates named histo-blood group antigens (HBGAs) are known (co)receptors for HuNoV.
Arno Cuvry +6 more
doaj +2 more sources
Norovirus–host interaction: Multi-selections by human histo-blood group antigens [PDF]
Trends in Microbiology, 2011 The discovery of human histo-blood group antigens (HBGAs) as receptors or ligands of noroviruses (NoVs) raises a question about the potential role of host factors in the evolution and diversity of NoVs. Recent structural analysis of selected strains in the two major genogroups of human NoVs (GI and GII) demonstrated highly conserved HBGA binding ...
Ming Tan, Xi Jiang
openalex +4 more sources
Histo-Blood Group Antigens in Oral Cancer and Potentially Malignant Disorders. [PDF]
Asian Pac J Cancer Prev, 2020 Early detection of oral cancer is of critical importance because survival rates markedly improve when oral lesions are identified at an early stage. Aim of the present study is to investigate the expression of ABO (H) antigens in tissue specimens of oral cancer and potentially malignant disorders and to determine the role of ABO (H) antigens in tumour ...
Pokala A +5 more
europepmc +4 more sources
Histo-Blood Group Antigen Assay for Detecting Noroviruses in Water [PDF]
Applied and Environmental Microbiology, 2020 ABSTRACT We evaluated a novel, magnetic-bead-based histo-blood group antigen assay for the recovery of low numbers of norovirus particles. Using this assay, with Norwalk virus seeded in environmental waters as a model, we were able to recover 30 to 300 genomic copies of the virus.
J. L. Cannon, J. Vinje
openalex +3 more sources
Interaction between noroviruses and human histo-blood group antigens
Uirusu, 2007 Norovirus (NOV), a member of the family Caliciviridae, is a major cause of water and food-borne acute nonbacterial gastroenteritis, and forms many morphologically similar but antigenically diverse groups of viruses. The virus-like particles (VLPs) derived from the prototype strain of NoV, Norwalk virus (NV/68), bind to histo-blood group antigens (HBGAs)
Haruko Shirato-Horikoshi, Naokazu Takeda
openalex +4 more sources
Histo-Blood Group Antigen-Producing Bacterial Cocktail Reduces Rotavirus A, B, and C Infection and Disease in Gnotobiotic Piglets [PDF]
VirusesThe suboptimal performance of rotavirus (RV) vaccines in developing countries and in animals necessitates further research on the development of novel therapeutics and control strategies.
Sergei A. Raev +5 more
doaj +2 more sources
Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. [PDF]
PLoS Pathogens, 2020 Initial cell attachment of rotavirus (RV) to specific cell surface glycan receptors, which is the essential first step in RV infection, is mediated by the VP8* domain of the spike protein VP4.
Shenyuan Xu +10 more
doaj +2 more sources
Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus infection. [PDF]
J Biol Chem, 2020 Rimkute I +12 more
europepmc +3 more sources