Minimizing the Entropy Penalty for Ligand Binding: Lessons from the Molecular Recognition of the Histo Blood-Group Antigens by Human Galectin-3. [PDF]
Angew Chem Int Ed Engl, 2019 Ligand conformational entropy plays an important role in carbohydrate recognition events. Glycans are characterized by intrinsic flexibility around the glycosidic linkages, thus in most cases, loss of conformational entropy of the sugar upon complex ...
Gimeno A +11 more
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The effect of proteolytic enzymes and pH on GII.4 norovirus, during both interactions and non-interaction with Histo-Blood Group Antigens. [PDF]
Sci Rep, 2020 Human noroviruses (HuNoVs) are the leading cause of acute gastroenteritis worldwide. Histo-Blood Groups Antigens (HBGAs) have been described as attachment factors, promoting HuNoV infection. However, their role has not yet been elucidated.
Chassaing M +7 more
europepmc +2 more sources
Histo-blood group antigens and rotavirus vaccine shedding in Nicaraguan infants. [PDF]
Sci Rep, 2019 ABO, Lewis and secretor histo-blood group antigens (HBGA) are susceptibility factors for rotavirus in a P-genotype dependent manner and can influence IgA seroconversion rates following rotavirus vaccination.
Bucardo F +6 more
europepmc +2 more sources
Biologic roles of the ABH and Lewis histo‐blood group antigens part II: thrombosis, cardiovascular disease and metabolism [PDF]
Vox Sanguinis, 2019 The ABH and Lewis antigens were among the first of the human red blood cell polymorphisms to be identified and, in the case of the former, play a dominant role in transfusion and transplantation.
Sean R. Stowell, Christopher P. Stowell
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The role of the blood group-related glycosyltransferases FUT2 and B4GALNT2 in susceptibility to infectious disease [PDF]
International Journal of Medical Microbiology, 2021 The glycosylation profile of the gastrointestinal tract is an important factor mediating host-microbe interactions. Variation in these glycan structures is often mediated by blood group-related glycosyltransferases, and can lead to wide-ranging ...
Alibek Galeev +5 more
doaj +3 more sources
Histo-blood group antigens as receptors for rotavirus, new understanding on rotavirus epidemiology and vaccine strategy. [PDF]
Emerg Microbes Infect, 2017 The success of the two rotavirus (RV) vaccines (Rotarix and RotaTeq) in many countries endorses a live attenuated vaccine approach against RVs. However, the lower efficacies of both vaccines in many low- and middle-income countries indicate a need to ...
Jiang X, Liu Y, Tan M.
europepmc +2 more sources
Functional and structural characterization of Norovirus GII.6 in recognizing histo-blood group antigens. [PDF]
Virol Sin, 2023 Cong X +7 more
europepmc +2 more sources
Effect of natural ageing and heat treatments on GII.4 norovirus binding to Histo-Blood Group Antigens. [PDF]
Sci Rep, 2019 Human noroviruses (HuNoVs) are the leading cause of viral foodborne outbreaks worldwide. To date, no available methods can be routinely used to detect infectious HuNoVs in foodstuffs.
Robin M +7 more
europepmc +2 more sources
Human Group C Rotavirus VP8*s Recognize Type A Histo-Blood Group Antigens as Ligands. [PDF]
J Virol, 2018 Group/species C rotaviruses (RVCs) have been identified as important pathogens of acute gastroenteritis (AGE) in children, family-based outbreaks, as well as animal infections. However, little is known regarding their host-specific interaction, infection,
Sun X +13 more
europepmc +2 more sources
Deciphering the role of histo-blood group antigens in bovine rotavirus C infection
bioRxivRotaviruses (RVs) are the main cause of viral diarrhea among infants, small children, and the young of many animal species. Histo-blood group antigens (HBGAs) are potential RV receptors and glycan composition on mucous surfaces influences host ...
Noemí Navarro-Lleó +10 more
openalex +2 more sources