Norovirus binding to intestinal epithelial cells is independent of histo-blood group antigens. [PDF]
Human noroviruses (NoVs) are a major cause of non-bacterial gastroenteritis. Although histo-blood group antigens (HBGAs) have been implicated in the initial binding of NoV, the mechanism of that binding before internalization is not clear.
Kosuke Murakami +11 more
doaj +2 more sources
Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens. [PDF]
Xu S +10 more
europepmc +3 more sources
Genetic Diversity and Histo-Blood Group Antigen Interactions of Rhesus Enteric Caliciviruses [PDF]
ABSTRACTRecently, we reported the discovery and characterization of Tulane virus (TV), a novel rhesus calicivirus (CV) (T. Farkas, K. Sestak, C. Wei, and X. Jiang, J. Virol.82:5408-5416, 2008). TV grows well in tissue culture, and it represents a new genus withinCaliciviridae, with the proposed name ofRecovirus. We also reported a high prevalence of CV
Tibor Farkas +5 more
openalex +4 more sources
Expression of histo-blood group antigens in bronchial squamous metaplasia [PDF]
The aim of the present study was to evaluate the expression of blood group antigens in squamous bronchial metaplasia in order to determine whether this factor could identify patients at risk of lung cancer.In total, 100 bronchial biopsies were included in the present study.
Nora Sánchez-Mora +4 more
openalex +4 more sources
Norovirus Capture with Histo-Blood Group Antigens Reveals Novel Virus-Ligand Interactions [PDF]
ABSTRACT Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States. Recent studies of norovirus attachment in vitro by using recombinant virus-like particles (VLPs) suggest that various norovirus strains exhibit ...
Patrick R. Harrington +3 more
openalex +3 more sources
Role of histo-blood group antigens in primate enteric calicivirus infections. [PDF]
Human noroviruses (NoV) are associated with large proportion of non-bacterial diarrhea outbreaks together with > 50% of food-associated diarrheas. The function of histo-blood group antigens (HBGAs) in pathogenesis of virus infection was implicated. Until recently however, due to lack of a robust animal and in vitro models of human NoV infection, only ...
Sestak K.
europepmc +3 more sources
Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides. [PDF]
ABSTRACT Human noroviruses interact with both human histo-blood group antigens (HBGAs) and human milk oligosaccharides (HMOs). The former are believed to be important for a virus infection, while the latter might act as natural decoys in the host during an infection. However, certain noroviruses are known to bind poorly to HBGAs and yet still
Schroten H, Hanisch FG, Hansman GS.
europepmc +5 more sources
Genogroup IV and VI canine noroviruses interact with histo-blood group antigens. [PDF]
ABSTRACT Human noroviruses (HuNV) are a significant cause of viral gastroenteritis in humans worldwide. HuNV attaches to cell surface carbohydrate structures known as histo-blood group antigens (HBGAs) prior to internalization, and HBGA polymorphism among human populations is closely linked to susceptibility to HuNV.
Caddy S +3 more
europepmc +4 more sources
Evolution of the interactions between GII.4 noroviruses and histo-blood group antigens: Insights from experimental and computational studies. [PDF]
Liang Y +8 more
europepmc +2 more sources
Attachment of Norovirus to Histo Blood Group Antigens: A Cooperative Multistep Process
AbstractHuman noroviruses recognize histo blood group antigens (HBGAs) as cellular attachment factors. Recently, it has been discovered that norovirus infection can be significantly enhanced by HBGA binding. Yet the attachment process and how it promotes host‐cell entry is only poorly understood.
Álvaro Mallagaray +4 more
openalex +6 more sources

