CAR T cells: the missing piece needed to improve outcomes for children with cancer? [PDF]
Mackall C.
europepmc +1 more source
Sero-typing of human lymphocyte antigens: Preliminary trials on long-term kidney homograft survivors [PDF]
Marchioro, TL, Starzl, TE, Terasaki, PI
core
A new method to identify proteins involved in the uptake and intracellular trafficking of nanoparticles is presented. After nanoparticle uptake, cells are lysed and the organelles with nanoparticles are purified using fluorescence assisted cell sorting. Next, their composition is determined by proteomic analysis.
Hector Garcia Romeu, Anna Salvati
wiley +1 more source
Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]
Pacini CP +5 more
europepmc +1 more source
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai +11 more
wiley +1 more source
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng +13 more
wiley +1 more source
Antibody-Dependent Cytotoxicity of Monocytes in Preeclampsia Is Associated with Soluble Forms of HLA. [PDF]
Krasnyi AM +8 more
europepmc +1 more source
The use of MHC class I or class II 'knock out' mice to investigate the role of these antigens in allosensitization [PDF]
Demetris, AJ +10 more
core
The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature. [PDF]
Jiang SM +6 more
europepmc +1 more source

