Pro-inflammatory responses after peptide-based cancer immunotherapy
HeliyonTherapeutic vaccinations are designed to prevent cancer by inducing immune responses against tumor antigens. in cancer cells, tumor-associated antigens (TAA) or tumor-specific (mutated) derived peptides are presented within the clefts of main ...
Hanie Mahaki +9 more
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The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Expression of Class I and Class II major histocompatibility complex antigens on epithelial cells in recurrent aphthous stomatitis [PDF]
, 1986 The concept of an immunopathogenesis in the establishment and progression of the recurrent aphthous stomatitis (RAS) lesion is well accepted. In this study the expression of Class I and Class II major histocompatibility complex (MHC) antigens on the ...
Seymour, G. J. +2 more
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The human leukocyte antigen system … simplified
Global Journal of Transfusion Medicine, 2017 Human leukocyte antigen (HLA) and transfusion medicine go hand in hand. Transfusion medicine experts are involved in transplants, particularly hematopoietic stem cell transplant.
Anand Deshpande
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Expression of Major Histocompatibility Complex Class II Antigen in Nod Mouse Thyroid
Autoimmunity, 1994 Non obese diabetic (NOD) mice spontaneously develop thyroiditis in addition to diabetes. Mononuclear cells begin to infiltrate the thyroid of these animals in the first month of life. The expression of major histocompatibility complex (MHC) class II (Ia) antigens by cells in the thyroid from NOD mice of various ages with and without thyroiditis was ...
H, Margolese +5 more
openaire +2 more sources
Animal Research and One Health, EarlyView.Depression accelerates tumor growth by dysregulation of tumor immune microenvironment. (A) Modeling methods: Subcutaneous tumor models were established under chronic unpredictable mild stress conditions, including cold swimming, physical restraint, and food/water deprivation, leading to increased tumor growth.
Yakun Ren +6 more
wiley +1 more source
Exploiting the retrograde transport of disarmed toxins for the delivery of exogenous antigens into MHC class 1 presentation pathway [PDF]
The targeting of exogenous antigen into the MHC class 1-restricted presentation pathway is required for the induction of cytotoxic T lymphocytes (CTL) which have been shown to be an important component of the protective response to intracellular ...
Noakes, Karen
core
The transmembrane domain of the adenovirus E3/19K protein acts as an ER retention signal and contributes to intracellular sequestration of MHC class I molecules [PDF]
, 2013 The human adenovirus E3/19K-protein is a type-I transmembrane glycoprotein of the endoplasmic reticulum (ER) that abrogates cell-surface transport of MHC class-I (MHC-I) and MICA/B-molecules.
Ruszics, Zsolt +3 more
core
In vitro expression of major histocompatibility class I and class II antigens by conditionally immortalized murine neural stem cells [PDF]
, 2003 The expression of major histocompatibility complex (MHC) antigens on the surface of cells is intimately linked to in vivo graft survival. It has been previously shown that the conditionally immortalized temperature-sensitive Maudsley hippocampal clone 36
Rezaie, P +5 more
core +1 more source
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2005 Se realizó un estudio de la frecuencia fenotípica y génica de los antígenos del sistema principal de histocompatibilidad HLA en personas no relacionadas, supuestamente sanas, tomadas como muestra de la población cubana.
Luz M Morera Barrios +8 more
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