Results 11 to 20 of about 63,782 (312)

The Class II Major Histocompatibility Complex Antigen Deficiency Syndrome: Consequences of Absent Class II Major Histocompatibility Antigens for Lymphocyte Differentiation and Function [PDF]

Journal of Investigative Dermatology, 1990
The class II major histocompatibility complex antigen deficiency syndrome is a rare immunodeficiency disease associated with defective expression of the class II antigens encoded for by the major histocompatibility complex. Clinically, this syndrome is manifest as a combined immunodeficiency presenting early in life, and affected individuals are ...
Clement, Loran T, Loran T Clement
openaire   +3 more sources

Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]

, 1997
Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Pieters, J., Watts, Colin, Knight, Andrew M., Colin Watts, Ferrari, Giorgio, Andrew M. Knight, Pieters, Jean, Ferrari, G., Watts, C., Jean Pieters, Giorgio Ferrari, Knight, A. M.   +11 more
core   +1 more source

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves, Griffin, D.K., Wesley C Warren, Edwards, Scott, Völker, Martin, Völker Martin, Westerdahl Helena, Burt, D.W., Graves, Tina, Griffin Darren K, Martin Völker, Burt, David W, Darren K Griffin, Helena Westerdahl, Godinez Ricardo, Edwards, S.V., Edwards, Scott V, Kotkiewicz, H., Ekblom, Robert,, Ekblom Robert, Warren, Wesley C, Warren, W.C., Ekblom, Robert, Robert Ekblom, David W Burt, Ricardo Godinez, Warren, Wesley C., Scott V Edwards, Lund University., Griffin, Darren K., Godinez, Ricardo, Westerdahl, Helena, Ekblom, R., Westerdahl, Helena,, Edwards, Scott V., Kotkiewicz, Holly, Voelker, Martin, Graves Tina, Christopher N Balakrishnan, Balakrishnan, Christopher N, Godinez, R., Warren Wesley C, Burt David W, Balakrishnan, Christopher N., Kotkiewicz Holly, Griffin, Darren K, Westerdahl, H., Balakrishnan Christopher N, Balakrishnan, C.N., Graves, T., Graves, Tina A., Burt, David W., Holly Kotkiewicz, Volker, M., Edwards Scott V   +54 more
core   +1 more source

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike, Bloemer, K, Messer, Gerald, Bloemer, Katharina, Messer, G, Ziegler, Andreas, Ragoussis, Jiannis, Ragoussis, J, Weiss, Elisabeth H., Pohla, H, Weiss, EH, Ziegler, A   +11 more
core   +1 more source

Herpesviruses Placating the Unwilling Host: Manipulation of the MHC Class II Antigen Presentation Pathway

Viruses, 2012
Lifelong persistent infection by herpesviruses depends on the balance between host immune responses and viral immune evasion. CD4 T cells responding to antigens presented on major histocompatibility complex class II (MHC-II) molecules are known to play ...
Martin Rowe, Jianmin Zuo
doaj   +1 more source

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef, Johnson, Judith P., Matthias Ulbrecht, Ulbrecht, Matthias, Josef Kellermann, Judith P. Johnson, Weiss, Elisabeth H., Elisabeth H. Weiss   +7 more
core   +1 more source

MHC-linked and un-linked class I genes in the wallaby [PDF]

, 2009
Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Wong, Emily S. W., Penny Coggill, Yuanyuan Cheng, Deakin Janine E, Katherine Belov, Hart, E., Janine E Deakin, Jennifer Harrow, Harrow Jennifer, Deakin, J.E., Cheng, Y., Beck, Stephan, Stephan Beck, Cheng, Yuanyuan, Hart, Elizabeth, Wong, Emily, Coggill, P., Deakin, Janine; id_orcid, Beck Stephan, Siddle, Hannah, Belov, K., Deakin, Janine E., Wong Emily SW, Hart Elizabeth, Wong, Emily Sw, Coggill Penny, Siddle, Hannah V., Wong, E.S.W., Coggill, Penny, Hannah V Siddle, Elizabeth Hart, Harrow, Jennifer, Beck, S., Cheng Yuanyuan, Harrow, J., Siddle Hannah V, Emily SW Wong, Belov Katherine, Siddle, H.V., Belov, Katherine   +39 more
core   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

Arquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN, Sinan SARI, Yaşar KANDUR, Buket DALGIÇ, Oğuz SÖYLEMEZOĞLU   +4 more
doaj   +1 more source

Comparative Reverse Vaccinology of Piscirickettsia salmonis, Aeromonas salmonicida, Yersinia ruckeri, Vibrio anguillarum and Moritella viscosa, Frequent Pathogens of Atlantic Salmon and Lumpfish Aquaculture

Vaccines, 2022
Marine finfish aquaculture is affected by diverse infectious diseases, and they commonly occur as co-infection. Some of the most frequent and prevalent Gram-negative bacterial pathogens of the finfish aquaculture include Piscirickettsia salmonis ...
Joy Chukwu-Osazuwa, Trung Cao, Ignacio Vasquez, Hajarooba Gnanagobal, Ahmed Hossain, Vimbai Irene Machimbirike, Javier Santander   +6 more
doaj   +1 more source

Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency

Allergy, Asthma & Clinical Immunology, 2012
Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and RFXAP. Defects
Djidjik Réda, Messaoudani Nesrine, Tahiat Azzedine, Meddour Yanis, Chaib Samia, Atek Aziz, Khiari Mohammed, Benhalla Nafissa, Smati Leila, Bensenouci Abdelatif, Baghriche Mourad, Ghaffor Mohammed   +11 more
doaj   +1 more source