Results 11 to 20 of about 105,385 (311)

Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Major histocompatibility complex (MHC) antigens are important for alloimmune responses as well as immune tolerance. Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon ...
Shuzi Zhang   +4 more
doaj   +1 more source

Modulation of the major histocompatibility complex class II-associated peptide repertoire by human histocompatibility leukocyte antigen (HLA)-DO [PDF]

open access: yes, 2000
Antigen presentation by major histocompatibility complex class II molecules is essential for antibody production and T cell activation. For most class II alleles, peptide binding depends on the catalytic action of human histocompatibility leukocyte ...
Adams   +47 more
core   +1 more source

Endogenous antigen presentation of MHC class II epitopes through non-autophagic pathways

open access: yesFrontiers in Immunology, 2015
Antigenic peptides presented by major histocompatibility complex (MHC) class II molecules are generally derived from exogenous proteins acquired by antigen presenting cells. However, in some circumstances, MHC class II molecules can present intracellular
Carol Sze Ki eLeung
doaj   +1 more source

Herpesviruses Placating the Unwilling Host: Manipulation of the MHC Class II Antigen Presentation Pathway

open access: yesViruses, 2012
Lifelong persistent infection by herpesviruses depends on the balance between host immune responses and viral immune evasion. CD4 T cells responding to antigens presented on major histocompatibility complex class II (MHC-II) molecules are known to play ...
Martin Rowe, Jianmin Zuo
doaj   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN   +4 more
doaj   +1 more source

Comparative Reverse Vaccinology of Piscirickettsia salmonis, Aeromonas salmonicida, Yersinia ruckeri, Vibrio anguillarum and Moritella viscosa, Frequent Pathogens of Atlantic Salmon and Lumpfish Aquaculture

open access: yesVaccines, 2022
Marine finfish aquaculture is affected by diverse infectious diseases, and they commonly occur as co-infection. Some of the most frequent and prevalent Gram-negative bacterial pathogens of the finfish aquaculture include Piscirickettsia salmonis ...
Joy Chukwu-Osazuwa   +6 more
doaj   +1 more source

Developmental and tissue-specific expression of the Q5k gene [PDF]

open access: yes, 1991
Expression of the Q5k gene was examined by northern blot analysis and polymerase chain reaction (PCR) in the AKR mouse and various cell lines, each of the H-2k haplotype.
Baeuerle, Patrick A.   +5 more
core   +1 more source

Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex

open access: yesEmerging Infectious Diseases, 1997
Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj   +1 more source

Interferon-gamma-activated macrophages infected with Burkholderia cenocepacia process and present bacterial antigens to T-cells by class I and II major histocompatibility complex molecules

open access: yesEmerging Microbes and Infections, 2020
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes   +10 more
doaj   +1 more source

Recognition of major histocompatibility complex antigens on cultured human biliary epithelial cells by alloreactive lymphocytes [PDF]

open access: yes, 1991
We have developed an in vitro system to study the interactions between biliary epithelium and lymphocytes using cultured human biliary epithelial cells.
Demetris, AJ   +5 more
core   +1 more source

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