Results 31 to 40 of about 63,510 (311)
Emerging Microbes and Infections, 2020 Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation into ...
Roberto Rosales-Reyes +10 more
doaj +1 more source
Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex
Emerging Infectious Diseases, 1997 Human leukocyte antigens (HLAs) are an inherent system of alloantigens, which are the products of genes of the major histocompatibility complex (MHC).
Neeloo Singh, S. Agrawal, A.K. Rastogi
doaj +1 more source
Acta Pharmaceutica Sinica B, 2023 Cancer vaccines represent a promising immunotherapeutic treatment modality. The promotion of cross-presentation of extracellular tumor-associated antigens on the major histocompatibility complex (MHC) class I molecules and dendritic cell maturation at ...
Aihua Wu +8 more
doaj +1 more source
Mediators of Inflammation, 1995 Major histocompatibility complex (MHC) class II antigen expression has been implicated in the pathogenesis of autoimmune type 1 diabetes. In this study we examined the role of various cytoldnes that may induce MHC class II surface antigen expression ...
S. Vassiliadis, G. K. Papadopoulos
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Antigen processing for MHC class II presentation via autophagy
Frontiers in Immunology, 2012 T cells recognize proteolytic fragments of antigens that are presented to them on major histocompatibility complex (MHC) molecules. MHC class I molecules present primarily products of proteasomal proteolysis to CD8+ T cells, while MHC class II molecules ...
Christian eMunz
doaj +1 more source
EXPRESSION OF A FUNCTIONAL CHIMERIC lg-MHC CLASS II PROTEIN [PDF]
, 1992 composed of the a- and ß-chains of the MHC class I1 I-E molecule fused to antibody V regions derived from anti-human CD4 mAb MT310. Expression vectors were constructed containing the functional, rearranged gene segments coding for the V region domains of
Zwirner, Jörg +8 more
core +1 more source
Is There any Greater Possibility in Finding HLA-identical Unrelated Hematopoietic Stem Cell Donors among Thalassemia Families for Transplantation of Thalassemia Patients? [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2004 Background: Thalassemia is probably the most common single gene disorder causing a major public health problem in the world. Currently, allogenic hematopoietic stem cell transplantation (HSCT) is the only curative therapy for thalassemia.
M Mohyeddin +5 more
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Cell Reports, 2022 Summary: Lentiviral vectors (LVs) are highly efficient at inducing CD8+ T cell responses. However, LV-encoded antigens are processed inside the cytosol of antigen-presenting cells, which does not directly communicate with the endosomal major ...
Jodie Lopez +14 more
doaj +1 more source
Antigen Presentation in the Gut
Canadian Journal of Gastroenterology, 1990 The induction of T cell responses requires recognition of antigens in association with class II major histocompatibility complex (MHC) proteins and specialized antigen-presenting cells.
W Doe, P Pavli
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E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]
, 2005 Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara +9 more
core +1 more source