Results 21 to 30 of about 63,510 (311)

Gene duplication and fragmentation in the zebra finch major histocompatibility complex [PDF]

open access: yes, 2010
BACKGROUND: Due to its high polymorphism and importance for disease resistance, the major histocompatibility complex (MHC) has been an important focus of many vertebrate genome projects.
Tina Graves   +54 more
core   +1 more source

Manipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells. [PDF]

open access: yesPLoS ONE, 2010
BACKGROUND: Major histocompatibility complex (MHC) antigens are important for alloimmune responses as well as immune tolerance. Previous studies have shown that presentation of donor MHC antigens by donor-specific transfusion prior to or upon ...
Shuzi Zhang   +4 more
doaj   +1 more source

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

open access: yes, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike   +11 more
core   +1 more source

Endogenous antigen presentation of MHC class II epitopes through non-autophagic pathways

open access: yesFrontiers in Immunology, 2015
Antigenic peptides presented by major histocompatibility complex (MHC) class II molecules are generally derived from exogenous proteins acquired by antigen presenting cells. However, in some circumstances, MHC class II molecules can present intracellular
Carol Sze Ki eLeung
doaj   +1 more source

Herpesviruses Placating the Unwilling Host: Manipulation of the MHC Class II Antigen Presentation Pathway

open access: yesViruses, 2012
Lifelong persistent infection by herpesviruses depends on the balance between host immune responses and viral immune evasion. CD4 T cells responding to antigens presented on major histocompatibility complex class II (MHC-II) molecules are known to play ...
Martin Rowe, Jianmin Zuo
doaj   +1 more source

Impaired Intracellular Transport and Cell Surface Expression of Nonpolymorphic HLA-E [PDF]

open access: yes, 1992
The assembly of the classical, polymorphic major histocompatibility complex class I molecules in the endoplasmic reticulum requires the presence of peptide ligands and ~2-microglobulin (~2m). Formation of this trimolecular complex is a prerequisite for e~
Kellermann, Josef   +7 more
core   +1 more source

MHC-linked and un-linked class I genes in the wallaby [PDF]

open access: yes, 2009
Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Wong, Emily S. W.   +39 more
core   +1 more source

EVALUATION OF HUMAN LEUKOCYTE ANTIGEN CLASS I AND II ANTIGENS IN HELICOBACTER PYLORI-POSITIVE PEDIATRIC PATIENTS WITH ACTIVE GASTRITIS AND DUODENAL ULCER

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: As being the first bacteria determined to be carcinogenic, Helicobacter pylori (H. pylori) is a pathogen localized in the stomach in more than half of the world population.
Sevim GÖNEN   +4 more
doaj   +1 more source

Comparative Reverse Vaccinology of Piscirickettsia salmonis, Aeromonas salmonicida, Yersinia ruckeri, Vibrio anguillarum and Moritella viscosa, Frequent Pathogens of Atlantic Salmon and Lumpfish Aquaculture

open access: yesVaccines, 2022
Marine finfish aquaculture is affected by diverse infectious diseases, and they commonly occur as co-infection. Some of the most frequent and prevalent Gram-negative bacterial pathogens of the finfish aquaculture include Piscirickettsia salmonis ...
Joy Chukwu-Osazuwa   +6 more
doaj   +1 more source

Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency

open access: yesAllergy, Asthma & Clinical Immunology, 2012
Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and RFXAP. Defects
Djidjik Réda   +11 more
doaj   +1 more source

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