Results 291 to 300 of about 108,384 (342)

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes

Immunology, EarlyView.
ERAP1 is an intracellular aminopeptidase that edits antigenic peptides to be presented by MHC class I molecules and is found in distinct functional allotypes in individuals. To investigate how different disease‐associated ERAP1 allotypes affect the cellular immunopeptidome, we generated A375 melanoma cell clones carrying either allotype 2 or allotype ...
Martha Nikopaschou, Martina Samiotaki, Anna Kannavou, Nikolaos V. Angelis, Ourania Tsitsilonis, George Panayotou, Efstratios Stratikos   +6 more
wiley   +1 more source

A machine learning-based method to optimize the immunogenicity of human leukocyte antigen class I-restricted neoantigens. [PDF]

Brief Bioinform
Zhang J, Zhou W, Yu J, Yan C, Liu J.
europepmc   +1 more source

Allogeneic orthotopic liver transplantation in mice: a preliminary study of rejection across well-defined MHC barriers. [PDF]

, 1991
Demetris, AJ, Fung, JJ, Qian, S, Starzl, TE   +3 more
core  

Interferon Regulatory Factor 2 (IRF2) Suppression Enhances Murine Cardiac Allograft Survival Through Immune Evasion

Immunology, EarlyView.
Our data show that suppressing IRF2, genetically or by siRNA, modulates PD‐L1 and MHC‐I levels. This induced immune‐evasive state critically underlies the significantly prolonged survival of cardiac allografts, revealing a novel therapeutic avenue.
Li Tian, Man Zhang, Yuliang Guo, Sheng Chang, Zhonghua Klaus Chen, Hongmin Zhou   +5 more
wiley   +1 more source

Research progress in RBC alloimmunization. [PDF]

Front Immunol
Fu Z, Hao X, Gao W, Wang Q.
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Immunopeptidome Landscape During <i>Brucella melitensis</i> Infection in Mice. [PDF]

Int J Mol Sci
Jin J, Sheng Y, Li T, Wang K, Geng F, Li Y, Gao J.   +6 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Immunogenetic diversity of MHC class II B-Lβ genes in Brazilian Caipiras (free-range) chickens laying blue eggs. [PDF]

Front Immunol
Costamilan CADVLR, Paludo E, Herkenhoff ME, Pértille F, de Souza ALS, Mendes CR, Dilarri G.   +6 more
europepmc   +1 more source

Universal CAR-T Cell Therapy for Cancer Treatment: Advances and Challenges. [PDF]

Oncol Res
Lei J, Ni Z, Zhang R.
europepmc   +1 more source