Results 61 to 70 of about 453,877 (390)

Regulation of major histocompatibility complex class II gene expression in trophoblast cells

open access: yesReproductive Biology and Endocrinology, 2004
Trophoblast cells are unique because they are one of the few mammalian cell types that do not express major histocompatibility complex (MHC) class II antigens, either constitutively or after exposure to IFN-γ.
Choi Jason C   +2 more
doaj   +1 more source

CD1-mediated immune responses in mucosal tissues: molecular mechanisms underlying lipid antigen presentation system

open access: yesExperimental and Molecular Medicine, 2023
The cluster of differentiation 1 (CD1) molecule differs from major histocompatibility complex class I and II because it presents glycolipid/lipid antigens. Moreover, the CD1-restricted T cells that recognize these self and foreign antigens participate in
Seohyun Kim, Sumin Cho, Ji Hyung Kim
doaj   +1 more source

Current advances in cancer vaccines targeting NY-ESO-1 for solid cancer treatment

open access: yesFrontiers in Immunology, 2023
New York-esophageal cancer 1 (NY-ESO-1) belongs to the cancer testis antigen (CTA) family, and has been identified as one of the most immunogenic tumor-associated antigens (TAAs) among the family members.
Hong Zhou   +13 more
doaj   +1 more source

Collective Classification of Textual Documents by Guided Self-Organization in T-Cell Cross-Regulation Dynamics [PDF]

open access: yesEvolutionary Intelligence. 2011. Volume 4, Number 2, 69-80, 2011
We present and study an agent-based model of T-Cell cross-regulation in the adaptive immune system, which we apply to binary classification. Our method expands an existing analytical model of T-cell cross-regulation (Carneiro et al. in Immunol Rev 216(1):48-68, 2007) that was used to study the self-organizing dynamics of a single population of T-Cells ...
arxiv   +1 more source

Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers. [PDF]

open access: yes, 2020
The study objective was to test the hypothesis that having histocompatible children increases the risk of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), possibly by contributing to the persistence of fetal cells acquired during ...
Barcellos, Lisa F   +16 more
core  

Comparison of the secondary structures of human class I and class II major histocompatibility complex antigens by Fourier transform infrared and circular dichroism spectroscopy.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1989
We have examined the secondary structures of human class I and class II histocompatibility antigens in solution by Fourier transform infrared spectroscopy and circular dichroism in order to compare the relative amounts of alpha-helix, beta-sheet, and ...
J. Gorga   +5 more
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Blood ties: ABO is a trans-species polymorphism in primates [PDF]

open access: yes, 2012
The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in all species sequenced to date.
arxiv   +1 more source

Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]

open access: yes, 2018
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar   +7 more
core   +6 more sources

Massive induction of donor-type class I and class II major histocompatibility complex antigens in rejecting cardiac allografts in the rat

open access: yesJournal of Experimental Medicine, 1985
DA (RT1a) hearts were transplanted into PVG (RT1c) or DA recipients, excised on days 1, 3, 5, or 7 after grafting, and examined by immunohistological techniques and quantitative absorption analyses, using allospecific mouse anti-rat class I and class II ...
A. Milton, J. Fabre
semanticscholar   +1 more source

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