Results 41 to 50 of about 570,523 (273)

Flavanols in the nuclei of the tea bush (Camellia sinensis) - broadening the perspectives to human health

Journal of Applied Botany and Food Quality, 2013
Flavanols as a small subclass of the flavonoids stain selectively blue with the special reagent p-dimethylaminocinnamaldehyde (DMACA). Because of the prominent blue colour it is easy to recognize the flavanols histochemically in the vacuoles of expanding
Jürgen Polster, Walter Feucht, Markus Schmid, H. Dithmar, Dieter Treutter   +4 more
doaj   +1 more source

Histones and histone modifications in protozoan parasites

Cellular Microbiology, 2006
Protozoan parasites are early branching eukaryotes causing significant morbidity and mortality in humans and livestock. Single-celled parasites have evolved complex life cycles, which may involve multiple host organisms, and strategies to evade host immune responses.
Sergio O. Angel, William J. Sullivan, Arunasalam Naguleswaran   +2 more
openaire   +2 more sources

A Proposal on Quantum Histone Modification in Gene Expression [PDF]

, 2012
A quantum mechanical model on histone modification is proposed. Along with the methyl / acetate or other groups bound to the modified residues the torsion angles of the nearby histone chain are supposed to participate in the quantum transition cooperatively.
arxiv   +1 more source

The histone database: A comprehensive resource for histones and histone fold‐containing proteins [PDF]

Proteins: Structure, Function, and Bioinformatics, 2005
AbstractTheThe Histone Database is a curated and searchable collection of full‐length sequences and structures of histones and nonhistone proteins containing histone‐like folds, compiled from major public databases. Several new histone fold‐containing proteins have been identified, including the huntingtin‐interacting protein HYPM.
Andreas D. Baxevanis, Leonardo Mariño-Ramírez, David Landsman, Benjamin Hsu   +3 more
openaire   +3 more sources

Actin and DNA protect histones from degradation by bacterial proteases but inhibit their antimicrobial activity

Frontiers in Microbiology, 2016
Histones are small polycationic proteins located in the cell nucleus. Together, DNA and histones are integral constituents of the nucleosomes. Upon apoptosis, necrosis and infection - induced cell death, histones are released from the cell.
Asaf Sol, Yaniv Skivrsky, Edna Blotnick, Gilad Bachrach, Andras Muhlrad   +4 more
doaj   +1 more source

The reduced expression of trimethylation of histone H3 at lysine 27 in primary cutaneous mucinous carcinoma

Dermatologica Sinica, 2023
Primary cutaneous mucinous carcinoma (PCMC) is rare, and its carcinogenesis is unclear. Trimethylation of histone H3 at lysine 27 (H3K27me3) is a key regulator in chromatin remodeling-controlled transcription.
Shu-Hao Li, Chien-Chun Chiou, Chien-Chin Chen   +2 more
doaj   +1 more source

DeepChrome 2.0: Investigating and Improving Architectures, Visualizations, & Experiments [PDF]

arXiv, 2022
Histone modifications play a critical role in gene regulation. Consequently, predicting gene expression from histone modification signals is a highly motivated problem in epigenetics. We build upon the work of DeepChrome by Singh et al. (2016), who trained classifiers that map histone modification signals to gene expression.
arxiv  

Histone deacetylases (HDACs): characterization of the classical HDAC family.

Biochemical Journal, 2003
Transcriptional regulation in eukaryotes occurs within a chromatin setting, and is strongly influenced by the post-translational modification of histones, the building blocks of chromatin, such as methylation, phosphorylation and acetylation. Acetylation
Annemieke J M de Ruijter, A. V. van Gennip, H. Caron, S. Kemp, A. V. van Kuilenburg   +4 more
semanticscholar   +1 more source

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma [PDF]

Frontiers in Cell and Developmental Biology, 2020
Histone deacetylases (HDACs) are enzymes that play a key role in regulating gene expression by remodeling chromatin structure. An imbalance of histone acetylation caused by deregulated HDAC expression and activity is known to promote tumor progression in a number of tumor types, including neuroblastoma, the most common solid tumor in children ...
Monica Phimmachanh, Sharissa L. Latham, Sharissa L. Latham, Jeremy Z. R. Han, David R. Croucher, David R. Croucher, Yolande E. I. O’Donnell   +6 more
openaire   +4 more sources

Further biochemical characterization of Mycobacterium leprae laminin-binding proteins

Brazilian Journal of Medical and Biological Research, 2001
It has been demonstrated that the alpha2 chain of laminin-2 present on the surface of Schwann cells is involved in the process of attachment of Mycobacterium leprae to these cells. Searching for M. leprae laminin-binding molecules, in a previous study we
M.A.M. Marques, S. Mahapatra, E.N. Sarno, S. Santos, J.S. Spencer, P.J. Brennan, M.C.V. Pessolani   +6 more
doaj   +1 more source