Results 21 to 30 of about 202,604 (264)
Early Life Stress- and Drug-Induced Histone Modifications Within the Ventral Tegmental Area
Frontiers in Cell and Developmental Biology, 2020 Psychiatric illnesses are a major public health concern due to their prevalence and heterogeneity of symptom presentation resulting from a lack of efficacious treatments.
Ryan D. Shepard, Fereshteh S. Nugent
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DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139*
Journal of Biological Chemistry, 1998 When mammalian cell cultures or mice are exposed to ionizing radiation in survivable or lethal amounts, novel mass components are found in the histone H2A region of two-dimensional gels.
E. Rogakou +4 more
semanticscholar +1 more source
Histones, histone chaperones and nucleosome assembly [PDF]
Protein & Cell, 2010 Chromatin structure governs a number of cellular processes including DNA replication, transcription, and DNA repair. During DNA replication, chromatin structure including the basic repeating unit of chromatin, the nucleosome, is temporarily disrupted, and then reformed immediately after the passage of the replication fork.
Rebecca J, Burgess, Zhiguo, Zhang
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Molecules, 2018 With the increasing interest in scarce proteins, reducing the sample volume for circular dichroism (CD) spectroscopy has become desirable. Demagnification of the incident beam size is required to reduce the sample volume for CD spectroscopy detecting ...
Yudai Izumi, Koichi Matsuo
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Histone-Histone Interactions and Centromere Function [PDF]
Molecular and Cellular Biology, 2000 Cse4p is a structural component of the core centromere of Saccharomyces cerevisiae and is a member of the conserved CENP-A family of specialized histone H3 variants. The histone H4 allele hhf1-20 confers defects in core centromere chromatin structure and mitotic chromosome transmission.
L, Glowczewski +4 more
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Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer
Nature Communications, 2017 Acetylation of the histone variant H2A.Z at gene promoters is associated with oncogene activation; however, it is unclear if such modification has a role in regulating the function of enhancers.
Fátima Valdés-Mora +18 more
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Frontiers in Endocrinology, 2018 Gonadotropin-releasing hormone (GnRH) stimulates the expression of multiple genes in the pituitary gonadotropes, most notably to induce synthesis of the gonadotropins, luteinizing hormone (LH), and follicle-stimulating hormone (FSH), but also to ensure ...
Philippa Melamed +6 more
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Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues
Nature Biotechnology, 2021 In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput.
Marek Bartošovič +2 more
semanticscholar +1 more source
The Secret Language of Destiny: Stress Imprinting and Transgenerational Origins of Disease
Frontiers in Genetics, 2012 Epigenetic regulation modulates gene expression without altering the DNA sequence to facilitate rapid adjustments according to current environmental conditions.
Fabiola Cristina Ribeiro Zucchi +3 more
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Molecular Insights into Epigenetics and Cannabinoid Receptors
Biomolecules, 2022 The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N-arachidonylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), their ...
Balapal S. Basavarajappa +1 more
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