Results 21 to 30 of about 557,726 (316)

Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription [PDF]

, 2014
Post-translational modifications of proteins have emerged as a major mechanism for regulating gene expression. However, our understanding of how histone modifications directly affect chromatin function remains limited.
Holzner, M. (M), Eleni Kallis, Holzner, M., Michaelis, J., Richter, F. (F) M. (M), Ryan, D. (D) P. (P), Feldmann, A. (A), Daniel P Ryan, Owen-Hughes, Tom; id_orcid, Kacem, S., Tropberger, Philipp, Di Cerbo, V., Bannister, A., Kallis, E. (E), Michaelis, Jens, Feldmann, A., Richter, Florian, Martin, Daujat, S. (Sylvain), Robert Schneider, Richter, F., Tropberger, P., Hoerner, Leslie, Richter, Florian Martin, Mittler, G. (G), Emilie Montellier, Di Cerbo, V. (V), Feil, Robert, Bannister, A. (A) J. (J), Vincenzo Di Cerbo, Ryan, D., Kallis, Eleni, Ryan, D. P., Di Cerbo, Vincenzo, Owen-Hughes, T. (T), Leslie Hoerner, Jens Michaelis, Kallis, E., Khochbin, S. (S), Saadi Khochbin, Schneider, Robert, Holzner, Monika, Monika Holzner, Feil, R. (R), Ryan, Daniel, P., Feldmann, Angelika, Tom Owen-Hughes, Owen-Hughes, T., Bannister, A. J., Feil, R., Mohn, F., Hoerner, L., Fabio Mohn, Richter, F. M., Montellier, E. (E), Mittler, G., Schuebeler, D., Montellier, Emilie, Mohn, F. (F), Tropberger, P. (P), Angelika Feldmann, Owen-Hughes, Tom, Kacem, Salim, Mittler, Gerhard, Daujat, Sylvain, Montellier, E., Schneider, R., Dirk Schuebeler, Schuebeler, D. (D), Bannister, Andrew J., Hoerner, L. (L), Khochbin, S., Schneider, R. (Robert), Schuebeler, Dirk, Salim Kacem, Philipp Tropberger, Mohn, Fabio, Florian Martin Richter, Kacem, S. (S), Sylvain Daujat, Ryan, Daniel P., Andrew J Bannister, Khochbin, Saadi, Gerhard Mittler, Michaelis, J. (J), Robert Feil, Daujat, S.   +85 more
core   +1 more source

The Secret Language of Destiny: Stress Imprinting and Transgenerational Origins of Disease

Frontiers in Genetics, 2012
Epigenetic regulation modulates gene expression without altering the DNA sequence to facilitate rapid adjustments according to current environmental conditions.
Fabiola Cristina Ribeiro Zucchi, Youli eYao, Youli eYao, Gerlinde A.S. Metz   +3 more
doaj   +1 more source

Histone methylation by PRC2 is inhibited by active chromatin marks [PDF]

, 2013
Chromatin modifiers serve as regulatory switches that control the cell cycle, maintain pluripotency and drive differentiation and development. Positive feedback mechanisms help to pass on transcriptional information from one generation of cells to the ...
Schmitges, Frank W.
core   +1 more source

Molecular Insights into Epigenetics and Cannabinoid Receptors

Biomolecules, 2022
The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS). ECS consists of the naturally occurring ligands N-arachidonylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG), their ...
Balapal S. Basavarajappa, Shivakumar Subbanna   +1 more
doaj   +1 more source

Histone modifications influence the action of Snf2 family remodelling enzymes by different mechanisms [PDF]

, 2007
Alteration of chromatin structure by chromatin modifying and remodelling activities is a key stage in the regulation of many nuclear processes. These activities are frequently interlinked, and many chromatin remodelling enzymes contain motifs that ...
Owen-Hughes, Tom; id_orcid, Flaus, Andrew, Ferreira, Helder, Owen-Hughes, Tom   +3 more
core   +1 more source

MicroRNAs as new Characters in the Plot between Epigenetics and Prostate Cancer

Frontiers in Genetics, 2011
Prostate cancer (PCA) still represents a leading cause of death. An increasing number of studies have documented that microRNAs (miRNAs), a subgroup of non-coding RNAs with gene regulatory functions, are differentially expressed in PCA respect to the ...
Alessio ePaone, Roberta eGalli, Muller eFabbri   +2 more
doaj   +1 more source

Complex exon-intron marking by histone modifications is not determined solely by nucleosome distribution [PDF]

, 2010
It has recently been shown that nucleosome distribution, histone modifications and RNA polymerase II (Pol II) occupancy show preferential association with exons (“exon-intron marking”), linking chromatin structure and function to co-transcriptional ...
Ellis Peter, Foad, NS, Christoph M Koch, Saffrey Peter, Dillon, SC, Alexander W Bruce, Dunham Ian, Bruce, A.W., Christoph M. Koch, Shane C. Dillon, Ellis, P, Saffrey, P., Chiang, K., Bye, J., Saffrey, P, James, K, James Keith, Watkins Nicholas A., Dhami, P., Watkins, N.A., Nicholas A. Watkins, Langford, C., Andrews, R.M., Dhami, P, Watkins, NA, Alexander W. Bruce, Bonhoure Nicolas, David Vetrie, Langford, C, Willem H Ouwehand, Chiang Kelly, Langford Cordelia, James, K., Pawandeep Dhami, Dunham, I., Vetrie David, Peter Saffrey, Bye, J, Ouwehand, W.H., Kelly Chiang, Foad Nicola S., Bonhoure, N, Andrews, RM, Willem H. Ouwehand, Shane C Dillon, Nicholas A Watkins, Cordelia Langford, Jackie Bye, Vetrie, D., Koch Christoph M., Bonhoure, N., Nicola S Foad, Koch, CM, Robert M Andrews, Keith James, Peter Ellis, Chiang, K, Ian Dunham, Dillon, S.C., Bruce Alexander W., Andrews Robert M., Dunham, I, Robert M. Andrews, Bye Jackie, Vetrie, D, Foad, N.S., Ellis, P., Bruce, AW, Ouwehand Willem H., Nicolas Bonhoure, Nicola S. Foad, Koch, C.M., Dillon Shane C., Ouwehand, WH, Wutz, A., Dhami Pawandeep   +75 more
core   +2 more sources

The reduced expression of trimethylation of histone H3 at lysine 27 in primary cutaneous mucinous carcinoma

Dermatologica Sinica, 2023
Primary cutaneous mucinous carcinoma (PCMC) is rare, and its carcinogenesis is unclear. Trimethylation of histone H3 at lysine 27 (H3K27me3) is a key regulator in chromatin remodeling-controlled transcription.
Shu-Hao Li, Chien-Chun Chiou, Chien-Chin Chen   +2 more
doaj   +1 more source

The Histone Database: an integrated resource for histones and histone fold-containing proteins [PDF]

Database, 2011
Eukaryotic chromatin is composed of DNA and protein components-core histones-that act to compactly pack the DNA into nucleosomes, the fundamental building blocks of chromatin. These nucleosomes are connected to adjacent nucleosomes by linker histones. Nucleosomes are highly dynamic and, through various core histone post-translational modifications and ...
Leonardo Mariño-Ramírez, Kevin M. Levine, Mario Morales, Suiyuan Zhang, Travis Moreland, Andreas D. Baxevanis, David Landsman   +6 more
openaire   +2 more sources

Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast [PDF]

, 2010
Histone modifications and the HtrA-like serine protease Nma111p regulate apoptosis in budding yeast David Walter, 2010, PhD Thesis, University of Basel Apoptosis is a form of programmed cell death that plays a central role in development and ...
Walter, David
core   +1 more source