Results 21 to 30 of about 427,828 (268)

The reduced expression of trimethylation of histone H3 at lysine 27 in primary cutaneous mucinous carcinoma

open access: yesDermatologica Sinica, 2023
Primary cutaneous mucinous carcinoma (PCMC) is rare, and its carcinogenesis is unclear. Trimethylation of histone H3 at lysine 27 (H3K27me3) is a key regulator in chromatin remodeling-controlled transcription.
Shu-Hao Li   +2 more
doaj   +1 more source

Epigenetic Alterations in Human Papillomavirus-Associated Cancers

open access: yesViruses, 2017
Approximately 15–20% of human cancers are caused by viruses, including human papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins that reprogram the regulatory networks governing host cellular signaling pathways ...
David Soto   +2 more
doaj   +1 more source

The histone database: A comprehensive resource for histones and histone fold‐containing proteins [PDF]

open access: yesProteins: Structure, Function, and Bioinformatics, 2005
AbstractTheThe Histone Database is a curated and searchable collection of full‐length sequences and structures of histones and nonhistone proteins containing histone‐like folds, compiled from major public databases. Several new histone fold‐containing proteins have been identified, including the huntingtin‐interacting protein HYPM.
Leonardo, Mariño-Ramírez   +3 more
openaire   +2 more sources

Similarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a “Bookmarking” Oncoprotein that Alters the Host Cell Epigenotype?

open access: yesPathogens, 2012
EBNA1, a nuclear protein expressed in all EBV-associated neoplasms is indispensable for the maintenance of the viral episomes in latently infected cells.
Hans Helmut Niller, Janos Minarovits
doaj   +1 more source

Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis

open access: yesThe EMBO Reports, 2020
Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post-translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase, regulating the acetylation of both histone and non-histone proteins. However, the role of HAT1 in succinylation modulation remains unclear.
Guang Yang   +14 more
openaire   +3 more sources

Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity

open access: yesFrontiers in Immunology, 2018
Autoimmune diseases are a significant cause of debilitation and mortality globally and are in need of cost-effective therapeutics. Autophagy is a cellular pathway that facilitates immune modulation involved in both pathogen control and autoimmunity ...
Jessica C. Hargarten   +1 more
doaj   +1 more source

Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-β1 Stimulation

open access: yesFrontiers in Pharmacology, 2017
Introduction: Epigenetic regulation of fibrogenesis through post-translational histone modifications (marks) may be a key determinant of progression in renal disease. In this study, we examined the distribution and acquisition of histone 3 Lysine 9 (H3K9)
Timothy D. Hewitson   +8 more
doaj   +1 more source

Association of Histones With Coagulofibrinolytic Responses and Organ Dysfunction in Adult Post-cardiac Arrest Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundPatients successfully resuscitated from cardiac arrest often develop organ dysfunction caused by systemic inflammation and increased coagulation, leading to disseminated intravascular coagulation (DIC).
Asumi Mizugaki   +4 more
doaj   +1 more source

Flavanols in the nuclei of the tea bush (Camellia sinensis) - broadening the perspectives to human health

open access: yesJournal of Applied Botany and Food Quality, 2013
Flavanols as a small subclass of the flavonoids stain selectively blue with the special reagent p-dimethylaminocinnamaldehyde (DMACA). Because of the prominent blue colour it is easy to recognize the flavanols histochemically in the vacuoles of expanding
Jürgen Polster   +4 more
doaj   +1 more source

New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis

open access: yesFrontiers in Plant Science, 2019
As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy