Results 41 to 50 of about 202,604 (264)

Flavanols in the nuclei of the tea bush (Camellia sinensis) - broadening the perspectives to human health

open access: yesJournal of Applied Botany and Food Quality, 2013
Flavanols as a small subclass of the flavonoids stain selectively blue with the special reagent p-dimethylaminocinnamaldehyde (DMACA). Because of the prominent blue colour it is easy to recognize the flavanols histochemically in the vacuoles of expanding
Jürgen Polster   +4 more
doaj   +1 more source

New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis

open access: yesFrontiers in Plant Science, 2019
As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang   +3 more
doaj   +1 more source

Histone locus bodies: a paradigm for how nuclear biomolecular condensates control cell cycle regulated gene expression

open access: yesNucleus, 2023
Histone locus bodies (HLBs) are biomolecular condensates that assemble at replication-dependent (RD) histone genes in animal cells. These genes produce unique mRNAs that are not polyadenylated and instead end in a conserved 3’ stem loop critical for ...
Mark S. Geisler   +2 more
doaj   +1 more source

A Positive Feedback Loop between Inactive VHL-Triggered Histone Lactylation and PDGFRβ Signaling Drives Clear Cell Renal Cell Carcinoma Progression

open access: yesInternational Journal on Biological Sciences, 2022
Inactive von Hippel-Lindau (VHL) is linked to metabolic reprogramming and plays pivotal roles in the pathogenesis of clear cell renal cell carcinoma (ccRCC).
Jiefeng Yang   +13 more
semanticscholar   +1 more source

Pharmacological Inhibition of LSD1 for Cancer Treatment

open access: yesMolecules, 2018
Lysine-specific demethylase 1A (LSD1, also named KDM1A) is a demethylase that can remove methyl groups from histones H3K4me1/2 and H3K9me1/2. It is aberrantly expressed in many cancers, where it impedes differentiation and contributes to cancer cell ...
Guan-Jun Yang   +4 more
doaj   +1 more source

The role of histone modifications: from neurodevelopment to neurodiseases

open access: yesSignal Transduction and Targeted Therapy, 2022
Epigenetic regulatory mechanisms, including DNA methylation, histone modification, chromatin remodeling, and microRNA expression, play critical roles in cell differentiation and organ development through spatial and temporal gene regulation. Neurogenesis
Jisu Park   +3 more
semanticscholar   +1 more source

Crosstalk Between mRNA 3'-End Processing and Epigenetics

open access: yesFrontiers in Genetics, 2021
The majority of eukaryotic genes produce multiple mRNA isoforms by using alternative poly(A) sites in a process called alternative polyadenylation (APA).
Lindsey V. Soles, Yongsheng Shi
doaj   +1 more source

Histones and histone modifications in protozoan parasites

open access: yesCellular Microbiology, 2006
Protozoan parasites are early branching eukaryotes causing significant morbidity and mortality in humans and livestock. Single-celled parasites have evolved complex life cycles, which may involve multiple host organisms, and strategies to evade host immune responses.
William J, Sullivan   +2 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A short guide to histone deacetylases including recent progress on class II enzymes

open access: yesExperimental and Molecular Medicine, 2020
The interaction between histones and DNA is important for eukaryotic gene expression. A loose interaction caused, for example, by the neutralization of a positive charge on the histone surface by acetylation, induces a less compact chromatin structure ...
Suk-Youl Park, Jeong-Sun Kim
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy