Results 61 to 70 of about 570,523 (273)
Inferring coarse-grain histone-DNA interaction potentials from high-resolution structures of the nucleosome [PDF]
, 2014 The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex. Here, we propose a framework for the extraction of a nanoscale histone-DNA force-field from a collection of high-resolution structures, which may be adapted to
arxiv +1 more source
New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis
Frontiers in Plant Science, 2019 As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang +3 more
doaj +1 more source
Antibiotics, 2021 Correlation studies about NOD1 and histones have not been reported. In the present study, we report the functional correlation between NOD1 and the histone H2A variant in response to Streptococcus agalactiae infection.
Xiaoman Wu +4 more
doaj +1 more source
Histone Deacetylase Inhibitors as Anticancer Drugs
International Journal of Molecular Sciences, 2017 Carcinogenesis cannot be explained only by genetic alterations, but also involves epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic regulation of gene expression and is controlled by the balance between histone ...
T. Eckschlager +3 more
semanticscholar +1 more source
MicroRNAs as new Characters in the Plot between Epigenetics and Prostate Cancer
Frontiers in Genetics, 2011 Prostate cancer (PCA) still represents a leading cause of death. An increasing number of studies have documented that microRNAs (miRNAs), a subgroup of non-coding RNAs with gene regulatory functions, are differentially expressed in PCA respect to the ...
Alessio ePaone +2 more
doaj +1 more source
First report of root and crown rot caused by Dactylonectria novozelandica on strawberry in Uruguay
Agrociencia Uruguay, 2022 Since 2015, a high mortality rate of strawberry plants has been observed in the north of Uruguay related to crown and root diseases caused by a pathogens complex. In 2016, associated with the death of plants, Cylindrocarpon spp.
Micaela Vigliecca +4 more
doaj +1 more source
Life, 2023 Transcription is known to be substage-specific in meiotic prophase I. If transcription is reactivated in the mid pachytene stage in mammals when synapsis is completed, then this process is observed in the zygotene stage in insects.
Sergey Matveevsky +3 more
doaj +1 more source
Nucleic Acids Research, 2002 Histone proteins are often noted for their high degree of sequence conservation. It is less often recognized that the histones are a heterogeneous protein family. Furthermore, several classes of non-histone proteins containing the histone fold motif exist.
Daniel W. Sink +6 more
openaire +3 more sources
DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation
Cell Reports, 2021 Summary: Histone lysine methylation functions at the interface of the extracellular environment and intracellular gene expression. DOT1L is a versatile histone H3K79 methyltransferase with a prominent role in MLL-fusion leukemia, yet little is known ...
Tanjing Song +9 more
doaj
Structural basis for the Rad6 activation by the Bre1 N-terminal domain
eLife, 2023 The mono-ubiquitination of the histone protein H2B (H2Bub1) is a highly conserved histone post-translational modification that plays critical roles in many fundamental processes. In yeast, this modification is catalyzed by the conserved Bre1–Rad6 complex.
Meng Shi +9 more
doaj +1 more source