Results 291 to 300 of about 189,363 (327)

TCA cycle rewiring underpins implantation and histone acetylation programming

open access: yes
Kafkia E   +11 more
europepmc   +1 more source

SlPLT6 controls ripening initiation and quality traits through modulation of histone acetylation and methylation in tomato. [PDF]

open access: yesProc Natl Acad Sci U S A
He X   +15 more
europepmc   +1 more source

Sex-Related Differences in Histone Acetylation and Tumor Development in a 4-Nitroquinoline 1-Oxide and Ethanol-Induced Oral Squamous Cell Carcinoma Mouse Model. [PDF]

open access: yesJ Oral Pathol Med
Nazário WR   +9 more
europepmc   +1 more source
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Mycardial histone acetylation

Life Sciences, 1981
Abstract Myocardial histone acetylation was investigated in an isolated perfused heart preparation. Radioactive acetate rapidly accumulated in the intracellular compartment which preceded the covalent modification of histones. The acetylation of nucleohistones was rapid and reached a maximum during the first 20 min of perfusion.
P B, Taylor, E A, Cook
openaire   +2 more sources

Histone Acetylation and Histone Deacetylation

Molecular Biotechnology, 2002
Regulation of inflammatory gene transcription is controlled, at least in part, by the degree of local unwinding of nucleosomal DNA. This unwinding is regulated by histone acetylation--increased acetylation results in a more loosely wound structure allowing access of basal transcription factors and RNA polymerase II.
Kazuhiro, Ito, Ian M, Adcock
openaire   +2 more sources

Histone acetylation and disease

Cellular and Molecular Life Sciences, 2001
Differential acetylation of histones and transcription factors plays an important regulatory role in developmental processes, proliferation and differentiation. Aberrant acetylation or deacetylation leads to such diverse disorders as leukemia, epithelial cancers, fragile X syndrome and Rubinstein-Taybi syndrome.
S, Timmermann   +3 more
openaire   +2 more sources

Histone acetylation and cancer

Current Opinion in Genetics & Development, 1999
In the past year, several papers have been published which implicate a link between alterations in chromatin structure and the development of cancer. Both histone hyperacetylation and hypoacetylation appear to be important in the neoplastic process, depending on the target gene involved. In the case of colon cancer, induction of the p21 gene by histone
S Y, Archer, R A, Hodin
openaire   +2 more sources

Histone Acetylation in Neurodevelopment

Current Pharmaceutical Design, 2013
Post-translational modification of histones is a primary mechanism through which epigenetic regulation of DNA transcription does occur. Among these modifications, regulation of histone acetylation state is an important tool to influence gene expression.
Antonio, Contestabile, Silvia, Sintoni
openaire   +2 more sources

Patterns of histone acetylation

European Journal of Biochemistry, 1990
The N‐terminal domains of all four core histones are subject to reversible acetylation at certain lysine residues. This modification has been functionally linked to transcription, histone deposition at replication and to histone removal during spermatogenesis.
A W, Thorne   +4 more
openaire   +2 more sources

Genomewide histone acetylation microarrays

Methods, 2003
Histone acetylation and methylation are important regulators of gene activity. Chromatin immunoprecipitation (ChIP or ChrIP) has made it possible to examine not only the state of histone acetylation at a gene but also that of histone methylation and may soon be extended to other histone modifications such as phosphorylation and ubiquitination.
Daniel, Robyr, Michael, Grunstein
openaire   +2 more sources

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