Results 111 to 120 of about 182,599 (256)

Repression of GCN5 Histone Acetyltransferase Activity via Bromodomain-Mediated Binding and Phosphorylation by the Ku–DNA-Dependent Protein Kinase Complex

open access: green, 1998
Nickolai A. Barlev   +6 more
openalex   +1 more source

The Proprotein Convertase BLI‐4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans

open access: yesAging Cell, EarlyView.
In ADR‐induced longevity in C. elegans, neuronal BLI‐4 processes neuropeptides, which are then released with the assistance of UNC‐31 and GOLG‐2. ABSTRACT Dietary restriction (DR) is a well‐established method for extending lifespan across various species, including C. elegans.
Ping Wu   +3 more
wiley   +1 more source

The HOX Homeodomain Proteins Block CBP Histone Acetyltransferase Activity [PDF]

open access: green, 2001
Wei-Fang Shen   +3 more
openalex   +1 more source

Insights Into Cockayne Syndrome Type B: What Underlies Its Pathogenesis?

open access: yesAging Cell, EarlyView.
Cockayne Syndrome complementation group B (CS‐B) is a highly debilitating progeroid syndrome that often culminates in the death of patients before adulthood. This review explores the pathogenesis of CS‐B and proposes that a combination of DNA damage accumulation, transcriptional dysregulation, and mitochondrial dysfunction is its underlying cause ...
Ricardo Afonso‐Reis   +3 more
wiley   +1 more source

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