Results 141 to 150 of about 35,141 (364)
Histone acetyltransferases and external demands influence task switching in Temnothorax ants. [PDF]
Biol Lett, 2023 Kohlmeier P, Feldmeyer B, Foitzik S.
europepmc +1 more source
Mitochondria‐Nuclear Crosstalk: Orchestrating mtDNA Maintenance
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The mitochondria (mt) and nucleus engage in a dynamic bidirectional communication to maintain cellular homeostasis, regulating energy production, stress response, and cell fate. Anterograde signaling directs mt function, while retrograde signaling conveys metabolic and stress‐related changes from mt to the nucleus. Central to this crosstalk is
Ghazal Darfarin, Janice Pluth
wiley +1 more source
The Involvement of Histone H3 Acetylation in Bovine Herpesvirus 1 Replication in MDBK Cells
Viruses, 2018 During bovine herpesvirus 1 (BoHV-1) productive infection in cell cultures, partial of intranuclear viral DNA is present in nucleosomes, and viral protein VP22 associates with histones and decreases histone H4 acetylation, indicating the involvement of ...
Liqian Zhu +4 more
doaj +1 more source
A quantum spin approach to histone dynamics [PDF]
arXiv, 2009 Post-translational modifications of histone proteins are an important factor in epigenetic control that serve to regulate transcription, depending on the particular modification states of the histone proteins. We study the stochastic dynamics of histone protein states, taking into account a feedback mechanism where modified nucleosomes recruit enzymes ...
arxiv
The origin and utility of histone deacetylases [PDF]
, 1997 A large region of two distinct yeast histone deacetylases, RPD3 and HDA1, is highly homologous to several prokaryotic enzymes that catalyze reactions involving various acetylated substrates.
Khochbin, Saadi, Wolffe, Alan P
core +1 more source
Glia, EarlyView.Spatial transcriptomic analysis unravels the mechanisms by which HDACi ameliorates neuroinflammation and enhances neuroprotection by modulating the expression of microglial transcriptomes in the ischemic mouse brain. ABSTRACT Ischemic stroke significantly contributes to global morbidity and disability through a cascade of neurological responses ...
Kevin Jayaraj +5 more
wiley +1 more source
Cell Reports, 2017 Acetyl-CoA is a key metabolic intermediate with an important role in transcriptional regulation. The nuclear-cytosolic acetyl-CoA synthetase 2 (ACSS2) was found to sustain the growth of hypoxic tumor cells.
Vinay Bulusu +12 more
doaj +1 more source
Epigenetic Dynamics of Cell Reprogramming [PDF]
arXiv, 2014 Reprogramming is a process of transforming differentiated cells into pluripotent stem cells by inducing specific modifying factors in the cells. Reprogramming is a non-equilibrium process involving a collaboration at levels separated by orders of magnitude in time scale, namely transcription factor binding/unbinding, protein synthesis/degradation, and ...
arxiv
The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis
BMC Plant Biology, 2008 Background Histone acetyltransferases (HATs) play critical roles in the regulation of chromatin structure and gene expression. Arabidopsis genome contains 12 HAT genes, but the biological functions of many of them are still unknown.
Zhou Dao-Xiu +6 more
doaj +1 more source
A Novel Role of Cdk9/CyclinT2 complexes in skeletal muscle and Rhabdomyosarcoma cells [PDF]
, 2010 Cyclin dependent kinase 9 (Cdk9) is a member of the cyclin dependent kinase family. The regulatory units of Cdk9 are the T family Cyclins (T1, T2) and Cyclin K1.
Marchesi, Irene
core