Results 141 to 150 of about 24,866 (282)

The Role and Mechanisms of Histone Acetyltransferases in Arterial Lesions

Frontiers in Bioscience-Landmark
Cardiovascular and cerebrovascular diseases are among the leading causes of death worldwide. Development of these diseases occurs following pathological structural remodeling and functional changes in the vascular wall.
Qianfeng Jiang, Wenxing Li, Jiaying Diao, Yang Jiao   +3 more
doaj   +1 more source

Two distinct males absent on the first (MOF)-containing histone acetyltransferases are involved in the epithelial-mesenchymal transition in different ways in human cells. [PDF]

Cell Mol Life Sci, 2022
Wei T, Liu H, Zhu H, Chen W, Wu T, Bai Y, Zhang X, Miao Y, Wang F, Cai Y, Jin J.   +10 more
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Targeting histone deacetylases for the treatment of immune, endocrine and metabolic disorders

, 2009
The 'histone code' is a well-established hypothesis describing the idea that specific patterns of post-translational modifications to histones act like a molecular "code" recognised and used by non-histone proteins to regulate specific chromatin ...
Norris, S., Gray, Stephen G., O'Byrne, Kenneth J., Lawless, M. W.   +3 more
core   +1 more source

Transcriptional adapter ADA2 regulates yield and end‐use quality through liquid–liquid phase separation in wheat

Journal of Integrative Plant Biology, EarlyView.
The transcriptional adapter ADA2 interacts with the histone acetyltransferase GCN5 to regulate starch and storage protein content in wheat grains through histone acetylation. ADA2 undergoes phase separation and is modulated by GCN5, affecting histone acetyltransferase activity and gene transcription.
Xiaobang Zhang, Ruijie Zhang, Yuhan Zhang, Tao Yang, Longfei Wu, Yuan Cao, Jun Xiao, Jigang Li, Xin Gao, Xinyou Cao, Jie Liu, Mingming Xin, Yuan Zong, Zhongfu Ni, Qixin Sun, Yingyin Yao   +15 more
wiley   +1 more source

Progress of Acetylation Modification in Plants

Agronomy
Protein acetylation, a conserved post-translational modification, is collaboratively catalyzed by acetyltransferases and deacetylases and is widespread in plants.
Ruiqi Li, Xuezhong Li, Ying He, Xiaoyuan Chen, Jing Li, Chuxiong Zhuang   +5 more
doaj   +1 more source

Glucose derived carbon nanosphere (CSP) conjugated TTK21, an activator of the histone acetyltransferases CBP/p300, ameliorates amyloid-beta 1-42 induced deficits in plasticity and associativity in hippocampal CA1 pyramidal neurons. [PDF]

Aging Cell, 2022
Singh AK, Neo SH, Liwang C, Pang KKL, Leng JCK, Sinha SH, Shetty MS, Vasudevan M, Rao VJ, Joshi I, Eswaramoorthy M, Pavon MV, Sheila AR, Navakkode S, Kundu TK, Sajikumar S.   +15 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

EMF2 deficiency disrupts epigenetic and chromatin organization landscapes, blocking root regeneration competence in Arabidopsis

New Phytologist, EarlyView.
EMF2 mutation alters transcriptomic profiles in Arabidopsis calli while retaining responsiveness during root induction. Summary Plant de novo organogenesis depends on callus formation, yet the epigenetic mechanisms governing organ regeneration remain poorly understood.
Zhidan Wang, May Avraham, Tali Mandel, Leor Eshed Williams, Chang Liu   +4 more
wiley   +1 more source

Post‐Translational Control of TaFT1 by WAPO1 Ubiquitination Shapes Spike Architecture and Yield in Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT The florigen protein TaFT1 coordinately regulates heading time and spikelet number per spike (SNS), serving as a key yield determinant in wheat. However, how its stability is post‐translationally controlled in the shoot apical meristem remains unclear.
Yujie Jiang, Xiongtao Li, Yiqing Wang, Haoran Wang, Zhaoyan Chen, Chaoqun Dong, Xiangqing Liu, Xincheng Wang, Sufang Li, Weilong Guo, Yingyin Yao, Mingming Xin, Xingguo Ye, Zhongfu Ni, Qixin Sun, Jie Liu   +15 more
wiley   +1 more source