Results 1 to 10 of about 262,101 (201)
Histone Acetyltransferase p300 [PDF]
Definitions, 2020 Histone acetyltransferase p300 (2414 aa, ~264 kDa) is encoded by the human EP300 gene. This protein is involved in histone acetylation, transcriptional regulation and development.
semanticscholar +2 more sources
Histone Acetyltransferase KAT6B [PDF]
Definitions, 2020 Histone acetyltransferase KAT6B (2073 aa, ~231 kDa) is encoded by the human KAT6B gene. This protein plays a role in both histone acetylation and the regulation of transcription.
semanticscholar +2 more sources
The EMBO Reports, 2020 Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post‐translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase, regulating the acetylation of both histone and non‐histone proteins ...
Guang Yang +14 more
semanticscholar +4 more sources
Histone Acetyltransferase KAT2B [PDF]
Definitions, 2020 Histone acetyltransferase KAT2B (832 aa, ~93 kDa) is encoded by the human KAT2B gene. This protein is involved in both histone acetylation and transcriptional activation.
semanticscholar +2 more sources
Structure of the NuA4 histone acetyltransferase complex
Proceedings of the National Academy of Sciences of the United States of America, 2022 Nucleosome acetyltransferase of H4 (NuA4), one of two major histone acetyltransferase complexes in Saccharomyces cerevisiae specifically acetylates histone H2A and H4, resulting in increased transcriptional activity.
Roger D. Kornberg, Heqiao Zhang
exaly +3 more sources
The Histone Acetyltransferase CgHat1 Regulates Growth, Development, and Pathogenicity of Colletotrichum gloeosporioides [PDF]
Journal of FungiColletotrichum gloeosporioides causes anthracnose on a wide range of plants, resulting in serious economic losses worldwide. However, the molecular mechanisms underlying its pathogenicity still remain largely unknown. In the past 20 years, the importance
Binghong Jia +7 more
doaj +2 more sources
Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors
Nature Communications, 2017 A substantial obstacle in basic research is the use of poorly validated tool compounds with purported useful biological functions. Here, the authors systematically profile widely used histone acetyltransferase inhibitors and find that the majority are ...
Jayme L. Dahlin +14 more
doaj +2 more sources
Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease. [PDF]
PLoS ONE, 2014 Epigenetic modifications, particularly histone acetylation, have been implicated in Alzheimer's disease (AD). While previous studies have suggested that histone hypoacetylation may regulate the expression of genes associated with memory and learning in ...
Xi Lu +9 more
doaj +2 more sources