Results 21 to 30 of about 391,128 (337)
Enhancer of Acetyltransferase Chameau (EAChm) Is a Novel Transcriptional Co-Activator. [PDF]
PLoS ONE, 2015 Acetylation of nucleosomal histones by diverse histone acetyltransferases (HAT) plays pivotal roles in many cellular events. Discoveries of novel HATs and HAT related factors have provided new insights to understand the roles and mechanisms of histone ...
Takeya Nakagawa +6 more
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Tropomyosins, N-terminal acetylation and their impact on yeast cytoskeletal function: A characterisation of novel tropomyosins from N. crassa and the N-terminal acetyltransferase, Nat3p [PDF]
, 2009 PhDWhile the fundamental role of tropomyosins (Tms) in the maintenance of the actin cytoskeleton in yeast is established, details of their exact regulatory functions in lower eukaryotes remains to be deciphered.
Ebrahim, Seham
core +4 more sources
Quiescent and proliferative fibroblasts exhibit differential p300 HAT activation through control of 5-methoxytryptophan production. [PDF]
PLoS ONE, 2014 Quiescent fibroblasts possess unique genetic program and exhibit high metabolic activity distinct from proliferative fibroblasts. In response to inflammatory stimulation, quiescent fibroblasts are more active in expressing cyclooxygenase-2 and other ...
Huei-Hsuan Cheng +5 more
doaj +1 more source
Parasites & Vectors, 2023 Background Histone acetylation is involved in the regulation of stress responses in multiple organisms. Dermacentor silvarum is an important vector tick species widely distributed in China, and low temperature is a crucial factor restricting the ...
Tingwei Pei +8 more
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ACS Medicinal Chemistry Letters, 2020 The histone acetyltransferases, CREB binding protein (CBP) and EP300, are master transcriptional co-regulators that have been implicated in numerous diseases, such as cancer, inflammatory disorders, and neurodegeneration.
Jonathan E. Wilson +11 more
semanticscholar +1 more source
Journal of Big Data, 2022 Dynamic changes in epigenetic landscape reflect a critical command of lineage-specific gene expression. In an effort to discern the epigenetic regulatory networks of myogenic differentiation, we have used systematic and integrative approaches to explore ...
Yuan Li +4 more
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The Ada2/Ada3/Gcn5/Sgf29 histone acetyltransferase module
Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 2020 Histone post-translational modifications are essential for the regulation of gene expression in eukaryotes. Gcn5 (KAT2A) is a histone acetyltransferase that catalyzes the post-translational modification at multiple positions of histone H3 through the ...
Jose M. Espinola Lopez, Song Tan
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2023 Acetylation of lysine residues on histone tails is an important post-translational modification (PTM) that regulates chromatin dynamics to allow gene transcription as well as DNA replication and repair.
Tiina Viita, Jacques Côté
doaj +1 more source
Inhibition of histone acetyltransferase by glycosaminoglycans [PDF]
Journal of Cellular Biochemistry, 2008 AbstractHistone acetyltransferases (HATs) are a class of enzymes that participate in modulating chromatin structure and gene expression. Altered HAT activity has been implicated in a number of diseases, yet little is known about the regulation of HATs.
Jo Ann, Buczek-Thomas +4 more
openaire +2 more sources
Characterisation of Sulfolobus solfataricus Ard1, a promiscuous N-acetyltransferase [PDF]
, 2008 Compaction of DNA into chromatin is an important feature of every living cell. This compaction phenomenon is brought about and maintained by a variety of DNA binding proteins, which have evolved to suit the specific needs of the different cell types ...
Mackay, Dale Tara
core +2 more sources