Results 11 to 20 of about 391,128 (337)

Association with the origin recognition complex suggests a novel role for histone acetyltransferase Hat1p/Hat2p [PDF]

BMC Biology, 2007
Background Histone modifications have been implicated in the regulation of transcription and, more recently, in DNA replication and repair. In yeast, a major conserved histone acetyltransferase, Hat1p, preferentially acetylates lysine residues 5 and 12 ...
Greenblatt Jack F, Lewis Peter, Krogan Nevan, Guo Xinghua, Pogoutse Oxana, Suter Bernhard, Rine Jasper, Emili Andrew   +7 more
doaj   +2 more sources

The histone acetyltransferase p300 inhibitor C646 reduces pro-inflammatory gene expression and inhibits histone deacetylases [PDF]

Biochemical Pharmacology, 2015
Lysine acetylations are reversible posttranslational modifications of histone and non-histone proteins that play important regulatory roles in signal transduction cascades and gene expression.
T. van den Bosch, A. Boichenko, N. Leus, M. Ourailidou, H. Wapenaar, D. Rotili, A. Mai, A. Imhof, R. Bischoff, H. Haisma, F. Dekker   +10 more
semanticscholar   +3 more sources

Histone Acetyltransferase KAT6A [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Histone Acetyltransferase KAT8 [PDF]

Definitions, 2020

semanticscholar   +2 more sources

Genome-wide identification and expression analysis of histone deacetylase and histone acetyltransferase genes in response to drought in poplars [PDF]

BMC Genomics
Background Histone deacetylases (HDACs) and histone acetyltransferases (HATs) are involved in plant growth and development as well as in response to environmental changes, by dynamically regulating gene acetylation levels.
Huanhuan Li, Yao Chen, Yujie Dai, Le Yang, Sheng Zhang   +4 more
doaj   +2 more sources

Gcn5 histone acetyltransferase is present in the mitoplasts

Biology Open, 2019
In Saccharomyces cerevisiae the Lysine-acetyltransferase Gcn5 (KAT2) is part of the SAGA complex and is responsible for histone acetylation widely or at specific lysines.
Arianna Montanari, Manuela Leo, Veronica De Luca, Patrizia Filetici, Silvia Francisci   +4 more
doaj   +4 more sources

Latest Research Development in Histone Acetylation in the Pathogenesis of Asthma [PDF]

Zhongguo quanke yixue, 2022
Asthma is primarily marked by airway hyperresponsiveness, inflammation, and remodeling. Histone acetylation is one of the most common epigenetic modifications that regulates histone acetyltransferase and histone deacetylase, and imbalanced regulation may
CHEN Shaopeng, ZENG Minjuan, LAI Tianwen
doaj   +1 more source

Histone acetyltransferase TaHAG1 acts as a crucial regulator to strengthen salt tolerance of hexaploid wheat

Plant Physiology, 2021
A histone acetyltransferase contributes to salt tolerance by mediating reactive oxygen species production in hexaploid wheat, which is involved in salt stress adaptability of polyploidy wheat.
Mei Zheng, Jing-Chen Lin, Xing-Bei Liu, W. Chu, Jin-Peng Li, Yu-Jiao Gao, Ke-Xin An, Wanjun Song, Ming-Ming Xin, Yingyin Yao, Huiru Peng, Z. Ni, Qixin Sun, Zhaorong Hu   +13 more
semanticscholar   +1 more source

HAT1: Landscape of Biological Function and Role in Cancer

Cells, 2023
Histone modifications, as key chromatin regulators, play a pivotal role in the pathogenesis of several diseases, such as cancer. Acetylation, and more specifically lysine acetylation, is a reversible epigenetic process with a fundamental role in cell ...
Vincenza Capone, Laura Della Torre, Daniela Carannante, Mehrad Babaei, Lucia Altucci, Rosaria Benedetti, Vincenzo Carafa   +6 more
doaj   +1 more source

The BRCA2 is a histone acetyltransferase [PDF]

Oncogene, 1998
Patients carrying mutations in BRCA1 or BRCA2 tumor suppressor genes have shown to have high risk in developing breast and ovarian cancers. Two potential functions of BRCA2 were proposed which includes role in the regulation of transcription and also in DNA repair.
H, Siddique, J P, Zou, V N, Rao, E S, Reddy   +3 more
openaire   +2 more sources