Results 11 to 20 of about 56,937 (264)
UBR7 acts as a histone chaperone for post-nucleosomal histone H3. [PDF]
EMBO J, 2021 Histone chaperones modulate the stability of histones beginning from histone synthesis, through incorporation into DNA, and during recycling during transcription and replication. Following histone removal from DNA, chaperones regulate histone storage and degradation.
Hogan AK +16 more
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Journal of Integrative Neuroscience, 2023 Neurodevelopment is a highly regulated process that relies on the precise regulation of gene expression. Numerous epigenetic mechanisms contribute and cooperate to ensure the proper execution of developmental gene expression programs.
Karanveer S Johal +2 more
doaj +1 more source
Histones, histone chaperones and nucleosome assembly [PDF]
Protein & Cell, 2010 Chromatin structure governs a number of cellular processes including DNA replication, transcription, and DNA repair. During DNA replication, chromatin structure including the basic repeating unit of chromatin, the nucleosome, is temporarily disrupted, and then reformed immediately after the passage of the replication fork.
Rebecca J, Burgess, Zhiguo, Zhang
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The Saccharomyces cerevisiae histone chaperone Rtt106 mediates the cell cycle recruitment of SWI/SNF and RSC to the HIR-dependent histone genes. [PDF]
PLoS ONE, 2011 In Saccharomyces cerevisiae, three out of the four histone gene pairs (HTA1-HTB1, HHT1-HHF1, and HHT2-HHF2) are regulated by the HIR co-repressor complex.
Monica E Ferreira +2 more
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Histone transfer among chaperones [PDF]
Biochemical Society Transactions, 2012 The eukaryotic processes of nucleosome assembly and disassembly govern chromatin dynamics, in which histones exchange in a highly regulated manner to promote genome accessibility for all DNA-dependent processes. This regulation is partly carried out by histone chaperones, which serve multifaceted roles in co-ordinating the interactions of histone ...
Wallace H, Liu, Mair E A, Churchill
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Dynamic Activity of Histone H3-Specific Chaperone Complexes in Oncogenesis
Frontiers in Oncology, 2022 Canonical histone H3.1 and variant H3.3 deposit at different sites of the chromatin via distinct histone chaperones. Histone H3.1 relies on chaperone CAF-1 to mediate replication-dependent nucleosome assembly during S-phase, while H3.3 variant is ...
Ting Wen, Qiao Yi Chen
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Histone chaperones regulate histone exchange during transcription [PDF]
The EMBO Journal, 2007 Transcription by RNA polymerase II is accompanied by dynamic changes in chromatin, including the eviction/deposition of nucleosomes or the covalent modification of histone subunits. This study examined the role of the histone H3/H4 chaperones, Asf1 and HIR, in histone mobility during transcription, with particular focus on the histone exchange pathway,
Hye-Jin, Kim +4 more
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FACT modulates the conformations of histone H2A and H2B N-terminal tails within nucleosomes
Communications Biology, 2022 NMR experiments reveal distinct interactions of the histone chaperone, FACT, with the proximal and distal flexible histone H2A and H2B tails of the asymmetrically unwrapped nucleosome.
Yasuo Tsunaka +2 more
doaj +1 more source
Advanced Science, 2023 Chromatin homeostasis mediates essential processes in eukaryotes, where histone chaperones have emerged as major regulatory factors during DNA replication, repair, and transcription.
Pedro Buzón +5 more
doaj +1 more source
Cell Reports, 2021 Summary: Heterochromatin formation requires three distinct steps: nucleation, self-propagation (spreading) along the chromosome, and faithful maintenance after each replication cycle.
Magdalena Murawska +7 more
doaj +1 more source