Results 181 to 190 of about 17,972 (261)

Decoding GUN1 in plastid‐to‐nucleus signaling: what it doesn't, what it does, and why it matters

New Phytologist, Volume 251, Issue 1, Page 81-88, July 2026.
Publication history of plant GUN1 research. Summary Plastid‐to‐nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast‐localized PPR‐SMR protein, remains a central yet poorly understood component of this network.
Marco Wendler, Dario Leister, Tatjana Kleine   +2 more
wiley   +1 more source

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

Plant, Cell &Environment, Volume 49, Issue 7, Page 3500-3517, July 2026.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse, Łukasz Paweł Tarkowski, Martial Briand, David Lalanne, Nicolas W. G. Chen, Matthieu Barret, Jerome Verdier   +6 more
wiley   +1 more source

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. [PDF]

Genes Dev
Franklin R, Zhang B, Frazier J, Chen M, Do BT, Padayao S, Wu K, Vander Heiden MG, Vakoc CR, Roe JS, Ninova M, Murn J, Sykes DB, Cheloufi S.   +13 more
europepmc   +1 more source

Histone chaperones and the Rrm3p helicase regulate flocculation in S. cerevisiae. [PDF]

Epigenetics Chromatin, 2019
Rowlands H, Shaban K, Foster B, Proteau Y, Yankulov K.   +4 more
europepmc   +1 more source

Comprehensive Biophysical Profiling Evidences Self‐Oligomerization of Bacterially Expressed Pc Protein

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Polycomb (Pc), a core component of Polycomb Repressive Complex 1 (PRC1), is largely intrinsically disordered yet forms buffer‐ and concentration‐dependent higher‐order assemblies. Integrative biophysical analysis and cryo‐electron microscopy reveal dynamic, heterogeneous oligomers, whereas AlphaFold modeling suggests that structural organization is ...
Maria Zahid, Sabin Prajapati, Ghazaleh Alamdari, Kai Tittmann, Selin Kara   +4 more
wiley   +1 more source

Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato, Hanan Abumanhal‐Masarweh, Martí de Cabo, Pablo Guerra, Marilena Hadjidemetriou, Neus Lozano, Kostas Kostarelos   +6 more
wiley   +1 more source

T‐Cell Exhaustion in the Tumor Microenvironment: Subcellular Dysfunction, Pan‐Cancer Characteristics, and Therapeutic Interventions

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This study elucidates the mechanisms of subcellular multidimensional collapse in exhausted T cells. By specifically targeting the nucleus, mitochondria, and endoplasmic reticulum, strategic interventions can effectively remodel the compromised organelle network. This integrated approach drives comprehensive T cell resuscitation, ultimately establishing
Mingxing Wang, Wanhui Dong, Jian Chen, Zhangjie Zhou, Shujuan Fu, Tingting Wu, Haiyan Jiang, Zhiying Wang, Zhixian Zhong, Yi Zhong   +9 more
wiley   +1 more source

Epicardial adipose tissue‐linked leukotriene and cytokine signalling pathways – novel targets for prevention of obesity‐ and diabetes‐linked ventricular arrhythmia

The Journal of Physiology, EarlyView.
Kelly A. Aromolaran, Ademuyiwa S. Aromolaran   +1 more
wiley   +1 more source

Sex differences in brain glucose metabolism and Alzheimer's disease risk and progression

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Sex differences are increasingly recognized as central to the biology of Alzheimer's disease (AD), yet the mechanisms through which they shape brain metabolism and disease vulnerability remain incompletely understood. Brain glucose hypometabolism is a core hallmark of AD and emerges decades before clinical decline, but accumulating evidence ...
Marjan Ramezan, Aphrodite Demetriou, Sara Nicole Burke, Ivan Nalvarte, Andrew C. Shin   +4 more
wiley   +1 more source

Electrostatic forces govern the binding mechanism of intrinsically disordered histone chaperones. [PDF]

PLoS One, 2017
Liu C, Wang T, Bai Y, Wang J.
europepmc   +1 more source