Results 181 to 190 of about 33,260 (245)

Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging

Aging Cell, Volume 25, Issue 5, May 2026.
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong, Damola Adejoro, Christopher Winefield, Stephen L. W. On, Philip A. Wescombe, Arvind Subbaraj, Andrew Saunders, Venkata Chelikani   +7 more
wiley   +1 more source

The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells. [PDF]

Mol Cell, 2020
Huang TH, Fowler F, Chen CC, Shen ZJ, Sleckman B, Tyler JK.   +5 more
europepmc   +1 more source

Histone Density and Dynamics Shape Mitotic Chromatid Architecture in Xenopus Egg Extracts

Genes to Cells, Volume 31, Issue 3, May 2026.
Histone chaperones and chromatin remodelers modulate histone density and dynamics. The resulting local chromatin properties are integrated with DNA reconfiguration activities mediated by condensins and topoisomerase IIα to shape the global architecture of mitotic chromosomes.
Keishi Shintomi, Keita Ohsumi, Mari Iwabuchi, Tatsuya Hirano   +3 more
wiley   +1 more source

Metacaspases contribute to the cellular response to heat stress in a marine diatom

New Phytologist, Volume 250, Issue 4, Page 2357-2367, May 2026.
Summary Climate‐driven marine heatwaves (HW) are extreme, large‐scale events characterized by elevated ocean temperatures lasting from days to months. Despite their importance, little is known about the molecular mechanisms of algal response to marine HW. Recent studies suggest that metacaspases play an important role in thermotolerance.
Mai Sadeh, Daniella Schatz, Shifra Ben‐Dor, Avia Mizrachi, Shiri Graff van Creveld, Amichai Zafrin, Assaf Vardi   +6 more
wiley   +1 more source

Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2787-2810, May 2026.
ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu, Ludvig Larsson, Kun‐Ting Hsieh, Chun‐Ping Yu, Yi‐Hua Chen, Kai‐Hsuan Ding, Ho‐Chun Yang, Joakim Lundeberg, Chin‐Min Kimmy Ho, Shu‐Hsing Wu, Mei‐Yeh Jade Lu, Wen‐Hsiung Li   +11 more
wiley   +1 more source

SCL15 Promotes Seed Longevity Acquisition in Arabidopsis thaliana by Enhancing Antioxidant and Repair Mechanisms During Maturation

Physiologia Plantarum, Volume 178, Issue 3, May/June 2026.
ABSTRACT To ensure seed longevity and successful germination, orthodox seeds acquire protective and repair mechanisms during the late stage of seed development to counteract the detrimental effects of desiccation and subsequent rehydration, processes often associated with oxidative stress.
Ming‐Jun Gao, Cathy Coutu, Qi Chen, Myrtle Harrington, Rong Zhou, Dwayne Hegedus   +5 more
wiley   +1 more source

Advances and opportunities for computational interrogation of plant proteins

The Plant Journal, Volume 126, Issue 3, May 2026.
SUMMARY Plants exhibit remarkable biochemical and physiological diversity, and are capable of adapting to a wide range of environmental conditions and stresses. This complexity makes them essential systems for understanding how life responds to a changing climate.
Sarah M. Bohling, Shaila Musharoff, Laura H. Gunn   +2 more
wiley   +1 more source

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. [PDF]

Genes Dev
Franklin R, Zhang B, Frazier J, Chen M, Do BT, Padayao S, Wu K, Vander Heiden MG, Vakoc CR, Roe JS, Ninova M, Murn J, Sykes DB, Cheloufi S.   +13 more
europepmc   +1 more source

Histone chaperones and the Rrm3p helicase regulate flocculation in S. cerevisiae. [PDF]

Epigenetics Chromatin, 2019
Rowlands H, Shaban K, Foster B, Proteau Y, Yankulov K.   +4 more
europepmc   +1 more source

Histone Variant H3.3: A versatile H3 variant in health and in disease [PDF]

, 2016

core   +1 more source