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Functions Of The Histone Chaperone Nucleolin In Diseases
2007Alteration of nuclear morphology is often used by pathologist as diagnostic marker for malignancies like cancer. In particular, the staining of cells by the silver staining methods (AgNOR) has been proved to be an important tool for predicting the clinical outcome of some cancer diseases.
Storck, Sébastien +3 more
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Developmental roles of histone H3 variants and their chaperones
Trends in Genetics, 2013Animal development and lifetime potential exploit a balance between the stability and plasticity of cellular identity. Within the nucleus, this is controlled by an interplay involving lineage-specific transcription factors and chromatin dynamics. Histone H3 variants contribute to chromatin dynamics through the timing and sites of their incorporation ...
Dan Filipescu +2 more
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Histone Chaperones in Chromatin Dynamics
2007Histone chaperones are the histone interacting factors that stimulate histone transfer reaction without being a part of the final product. They are involved in the histone storage, histone translocation to the nucleus, and histone exchange and histone deposition onto the DNA for replication dependent chromatin assembly.
Jayasha, Shandilya +3 more
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Histone Chaperones, Epigenetics, and Cancer
2013Histone chaperones such as CAF1, ASF1, HIRA, DEK, DAXX, and several others play central roles in the transport, modification, replication, and replacement of nucleosomes. These diverse roles affect many processes including epigenetic memory, genome stability, transcription, Polycomb function, and others.
Mina Rafiei, Rod Bremner
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Analysis of Histone and Histone Chaperone Nuclear Import
2017The nuclear import of proteins is a fundamental process required for the proper formation and function of chromatin. Analysis of the nuclear import pathways of the histones, the major protein component of chromatin, and the histone chaperones that mediate their assembly into nucleosomes is important for understanding how chromatin assembly is regulated
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Histone chaperones and chromatin assembly
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2012openaire +2 more sources
Recent Perspectives on the Roles of Histone Chaperones in Transcription Regulation
Current Molecular Biology Reports, 2017B Ashok Reddy +2 more
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