Results 211 to 220 of about 66,376 (233)
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Reproduction, 2017
Abstract Meiosis is a specialized process that produces haploid gametes from diploid cells by a single round of DNA replication followed by two successive cell divisions. It contains many special events, such as programmed DNA double-strand break (DSB) formation, homologous recombination, crossover formation and resolution.
Lina, Wang +4 more
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Abstract Meiosis is a specialized process that produces haploid gametes from diploid cells by a single round of DNA replication followed by two successive cell divisions. It contains many special events, such as programmed DNA double-strand break (DSB) formation, homologous recombination, crossover formation and resolution.
Lina, Wang +4 more
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Is the “Histone Code” an Organic Code?
Biosemiotics, 2014Post-translational histone modifications and their biological effects have been described as a ‘histone code’. Independently, Barbieri used the term ‘organic code’ to describe biological codes in addition to the genetic code. He also provided the defining criteria for an organic code, but to date the histone code has not been tested against these ...
Stefan Kühn, Jan-Hendrik S. Hofmeyr
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Epigenetic Histone Code and Autoimmunity
Clinical Reviews in Allergy & Immunology, 2009The multiple inter-dependent post-translational modifications of histones represent fine regulators of chromatin dynamics. These covalent modifications, including phosphorylation, acetylation, ubiquitination, deimination, and methylation, affect therefore the numerous processes involving chromatin, such as replication, repair, transcription, genome ...
Dieker, Jürgen, Muller, Sylviane
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2018
Post-translational modifications of histones are frequent and important epigenetic signals that control many biological processes, such as cellular differentiation in the context of embryogenesis. Acetylations and methylations of lysines in histone tails are understood best and may be most important epigenetic marks, but there are also a number of ...
Carsten Carlberg, Ferdinand Molnár
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Post-translational modifications of histones are frequent and important epigenetic signals that control many biological processes, such as cellular differentiation in the context of embryogenesis. Acetylations and methylations of lysines in histone tails are understood best and may be most important epigenetic marks, but there are also a number of ...
Carsten Carlberg, Ferdinand Molnár
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Science's STKE, 2002
Chromatin plays an important role in the regulation of gene expression. Covalent modification of the tails of the histone proteins, which make up the nucleosome around which DNA is wrapped, can alter the response of a gene to the transcription machinery.
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Chromatin plays an important role in the regulation of gene expression. Covalent modification of the tails of the histone proteins, which make up the nucleosome around which DNA is wrapped, can alter the response of a gene to the transcription machinery.
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Science, 2017
Immunogenomics Epigenetic readers are proteins that recognize histone modifications and facilitate histone code–based transcriptional programming. Bromodomain- and plant homeodomain (PHD)–containing proteins often serve as readers of acetylation and methylation on histones, respectively. Mehta et al.
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Immunogenomics Epigenetic readers are proteins that recognize histone modifications and facilitate histone code–based transcriptional programming. Bromodomain- and plant homeodomain (PHD)–containing proteins often serve as readers of acetylation and methylation on histones, respectively. Mehta et al.
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Histone Deacetylases, the Erasers of the Code
2016The acetylation of the N-terminal tail domains of core histones provides a rich potential source of epigenetic information. Acetylation involves the addition of an acetyl group to a lysine residue by the action of the histone/lysine acetyltransferase enzymes (HATs/KATs).
Lamberti, María Julia +3 more
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Histone acetylation and an epigenetic code
BioEssays, 2000The enzyme-catalyzed acetylation of the N-terminal tail domains of core histones provides a rich potential source of epigenetic information. This may be used both to mediate transient changes in transcription, through modification of promoter-proximal nucleosomes, and for the longer-term maintenance and modulation of patterns of gene expression.
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The chromatin regulatory code: Beyond a histone code
The European Physical Journal E, 2006In this commentary on the contribution by Arndt Benecke in this issue, I discuss why the notion of "chromatin code" introduced and elaborated in this paper is to be preferred to that of "histone code". Speaking of a code as regards nucleosome conformation and histone tail post-translational modifications only makes sense within the chromatin fiber ...
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Science's STKE, 2007
The bacteria Shigella flexneri causes dysentery as a consequence of its infection of colonic epithelial cells. Arbibe et al . show that the mitogen-activated protein kinase kinase MEK1 was activated (phosphorylated) in HeKa cells infected with Shigella; however, activation (phosphorylation ...
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The bacteria Shigella flexneri causes dysentery as a consequence of its infection of colonic epithelial cells. Arbibe et al . show that the mitogen-activated protein kinase kinase MEK1 was activated (phosphorylated) in HeKa cells infected with Shigella; however, activation (phosphorylation ...
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