Results 31 to 40 of about 66,376 (233)
A Histone Code for Chromatin Assembly [PDF]
Cell, 2008 In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. (2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histone chaperones CAF-1 and Rtt106. Chen et al.
Fillingham, Jeffrey, Greenblatt, Jack F.
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Conservation and divergence of the histone code in nucleomorphs. [PDF]
Biol Direct, 2016 Nucleomorphs, the remnant nuclei of photosynthetic algae that have become endosymbionts to other eukaryotes, represent a unique example of convergent reductive genome evolution in eukaryotes, having evolved independently on two separate occasions in chlorarachniophytes and cryptophytes.
Marinov GK, Lynch M.
europepmc +4 more sources
Human Histone Demethylase LSD1 Reads the Histone Code [PDF]
Journal of Biological Chemistry, 2005 Human histone demethylase LSD1 is a flavin-dependent amine oxidase that catalyzes the specific removal of methyl groups from mono- and dimethylated Lys4 of histone H3. The N-terminal tail of H3 is subject to various covalent modifications, and a fundamental question in LSD1 biology is how these epigenetic marks affect the demethylase activity.
F. Forneris +4 more
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Epigenetics, cryptorchidism, and infertility
Basic and Clinical Andrology, 2023 Background Cryptorchid boys with defective mini-puberty and impaired differentiation of Ad spermatogonia (high infertility risk) have altered expression of several genes encoding histone methyltransferases compared to patients with intact differentiation
Faruk Hadziselimovic +2 more
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The PRC2 molecule EED is a target of epigenetic therapy for neuroblastoma
European Journal of Cell Biology, 2022 Epigenetic modifications by polycomb repressive complex (PRC) molecules appear to play a role in the tumorigenesis and aggressiveness of neuroblastoma (NB).
Dilibaerguli Shaliman +4 more
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Apoptotic phosphorylation of histone H3 on Ser-10 by protein kinase Cδ. [PDF]
PLoS ONE, 2012 Phosphorylation of histone H3 on Ser-10 is regarded as an epigenetic mitotic marker and is tightly correlated with chromosome condensation during both mitosis and meiosis.
Choon-Ho Park, Kyong-Tai Kim
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The Histone Modifications of Neuronal Plasticity
Neural Plasticity, 2021 Nucleosomes composed of histone octamer and DNA are the basic structural unit in the eukaryote chromosome. Under the stimulation of various factors, histones will undergo posttranslational modifications such as methylation, phosphorylation, acetylation ...
Huixia Geng +3 more
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Interplay of Histone Marks with Serine ADP-Ribosylation
Cell Reports, 2018 Summary: Serine ADP-ribosylation (Ser-ADPr) is a recently discovered protein modification that is catalyzed by PARP1 and PARP2 when in complex with the eponymous histone PARylation factor 1 (HPF1).
Edward Bartlett +6 more
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Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells. [PDF]
PLoS ONE, 2016 Bacterial lipopolysaccharide (LPS) induces release of inflammatory mediators both in immune and epithelial cells. We investigated whether changes of epigenetic marks, including selected histone modification and DNA methylation, may drive or accompany the
Tiziana Angrisano +11 more
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Finding combinatorial histone code by semi-supervised biclustering
BMC Genomics, 2012 Background Combinatorial histone modification is an important epigenetic mechanism for regulating chromatin state and gene expression. Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational ...
Teng Li, Tan Kai
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