Results 111 to 120 of about 123,729 (215)

Use of histone deacetylase inhibitors: Novel advances in cancer treatment

, 2020
Histone deacetylase inhibitors (HDACIs) are a reassuring group of anti-cancer drugs that alters the gene expression patterns of cancer cells through epigenetic modulation.
Dogantimur, Ozge
core  

Histone deacetylase enzyme activity is not the universal anticancer target of HDAC inhibitors. [PDF]

Signal Transduct Target Ther
Rai C, Ruan H, Li X, Li W, Jeong HH, Song C, Liu P, Chang Y, Fang H, Kumar S U, Sun Y, You MJ, Guan D, Liu Z, Han L, Hou X, Sun Z.   +16 more
europepmc   +1 more source

The Use of Histone Deacetylase Inhibitors: Novel Advances in Cancer Treatment

This thesis explores the role of histone deacetylase inhibitors (HDACis) as promising epigenetic therapies in cancer treatment. HDACis modulate gene expression by inhibiting histone deacetylases, leading to the reactivation of tumor suppressor genes ...
Raad , Lara
core  

Zinc Affinity of Benzamide-Based Histone Deacetylase Inhibitors: A DFT Study. [PDF]

Molecules
Toshev N, Velichkov K, Uzunova Y, Cheshmedzhieva D, Dudev T.   +4 more
europepmc   +1 more source

Screening and evaluation of potential histone deacetylase inhibitors against Babesia infections. [PDF]

Int J Parasitol Drugs Drug Resist
Zhang X, Li Y, Che J, Wang J, Liang Q, Zhang Y, Bai Y, Zhao S, Yin H, Wang J, Guan G.   +10 more
europepmc   +1 more source

Correction: Histone deacetylase inhibitors are protective in acute but not in chronic models of ototoxicity. [PDF]

Front Cell Neurosci
Yang CH, Liu Z, Dong D, Schacht J, Arya D, Sha SH.   +5 more
europepmc   +1 more source

Histone Deacetylase [PDF]

, 2020
openaire   +1 more source

Histone Deacetylase-2 Expression in Colorectal Cancer: An Immunohistochemical Study and Its Clinicopathological Significance. [PDF]

Cancers (Basel)
Garmpis N, Nonni A, Dimitroulis D, Effraimidou EI, Garmpi A, Papandroudis MP, Kontzoglou K, Damaskos C.   +7 more
europepmc   +1 more source

In vitro characterization of the catalytic domain of human histone deacetylase 5. [PDF]

Sci Rep
Mammen C, Hornung FM, Anzenhofer C, Schumacher J, Reiners J, Li J, Mazzone F, Bilsing FL, Kassack MU, Kurz T, Smits SHJ.   +10 more
europepmc   +1 more source

[Expression of Concern] Histone deacetylase inhibitors induce in human hepatoma HepG2 cells acetylation of p53 and histones in correlation with apoptotic effects. [PDF]

Int J Oncol
Carlisi D, Vassallo B, Lauricella M, Emanuele S, D'anneo A, Di Leonardo E, Di Fazio P, Vento R, Tesoriere G.   +8 more
europepmc   +1 more source