EXTH-11. HISTONE DEACETYLASE 6 (HDAC6) INHIBITORS RETARD CELL PROLIFERATION AND INDUCE ROBUST CELL DEATH IN GLIOBLASTOMA (GBM) CELLS AND GBM SPHEROIDS CONTAINING STEM CELLS [PDF]
, 2016 M. Reza Saadatzadeh
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Advances in targeting histone deacetylase for treatment of solid tumors
Journal of Hematology & OncologyHistone deacetylase (HDAC) serves as a critical molecular regulator in the pathobiology of various malignancies and have garnered attention as a viable target for therapeutic intervention.
Mu-Qi Shi +6 more
doaj +1 more source
Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors [PDF]
, 2022 L Bamberg +15 more
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The Broad Spectrum HDAC Inhibitor PCI-24781 Induces Caspase- and ROS-Dependent Apoptosis and is Synergistic with Bortezomib in Lymphoma [PDF]
, 2008 We investigated the cytotoxicity and biology of the novel broad-spectrum hydroxamic acid-based histone deacetylase inhibitor (HDACi), PCI-24781. PCI-24781 was studied alone and combined with bortezomib in Hodgkin lymphoma (L428) and non-Hodgkin's ...
Andrew Evens +9 more
core +1 more source
Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models [PDF]
, 2008 Shuzhen Liu +4 more
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International Journal of Radiation Oncology, Biology, Physics, 2015 A. Krauze +8 more
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Histone Deacetylase Inhibitors in Cancer
, 2018 Abdulrahman Mawadh A Alsubhi +1 more
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Chalcone Derivative B8HA as A Novel Histone Deacetylase and Tubulin Dual-targeting Inhibitors, Inhibits Triple-Negative Breast Cancer Cells Proliferation [PDF]
, 2022 kangkang li +4 more
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Intra-articular Histone Deacetylase Inhibitor Microcarrier Delivery to Reduce Osteoarthritis. [PDF]
Nano Lett, 2023 Ye J +8 more
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