Results 41 to 50 of about 18,790 (139)

SMYD family in cancer: epigenetic regulation and molecular mechanisms of cancer proliferation, metastasis, and drug resistance

Experimental and Molecular Medicine
Epigenetic modifiers (miRNAs, histone methyltransferases (HMTs)/demethylases, and DNA methyltransferases/demethylases) are associated with cancer proliferation, metastasis, angiogenesis, and drug resistance.
Tae-Su Han, Dae-Soo Kim, Mi-Young Son, Hyun-Soo Cho   +3 more
doaj   +1 more source

A convenient research strategy for functional verification of epigenetic regulators during spermatogenesis

Asian Journal of Andrology
Spermatogenesis is a fundamental process that requires a tightly controlled epigenetic event in spermatogonial stem cells (SSCs). The mechanisms underlying the transition from SSCs to sperm are largely unknown.
Shan Li, Ying Yuan, Ke-Yu Zhang, Yi-Dan Guo, Lu-Tong Wang, Xiao-Yuan Zhang, Shu Zhang, Qi Yan, Rong Zhang, Jie Chen, Feng-Tang Yang, Jing-Rui Li   +11 more
doaj   +1 more source

Purification of histone demethylases from HeLa cells [PDF]

, 2006
Y TSUKADA, Yi Zhang
openalex   +1 more source

LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond

Biomolecules
Histone demethylases, enzymes responsible for removing methyl groups from histone proteins, have emerged as critical players in regulating gene expression and chromatin dynamics, thereby influencing various cellular processes.
Hyun-Min Kim, Zifei Liu
doaj   +1 more source

A Novel Histone H3K9 Demethylase JHDM2A Offers Clues About Androgen Receptor Regulation and Prostate Cancer Therapy [PDF]

, 2006

openalex   +1 more source

Recent developments in catalysis and inhibition of the Jumonji histone demethylases. [PDF]

Curr Opin Struct Biol, 2023
Sarah L, Fujimori DG.
europepmc   +1 more source

Small molecule KDM4s inhibitors as anti-cancer agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Histone demethylation is a vital process in epigenetic regulation of gene expression. A number of histone demethylases are present to control the methylated states of histone.
Hongzhi Lin, Qihang Li, Qi Li, Jie Zhu, Kai Gu, Xueyang Jiang, Qianqian Hu, Feng Feng, Wei Qu, Yao Chen, Haopeng Sun   +10 more
doaj   +1 more source

The Histone H3 Lysine-27 Demethylase Jmjd3 Links Inflammation to Inhibition of Polycomb-Mediated Gene Silencing [PDF]

, 2007
Francesca De Santa, Maria Grazia Totaro, Elena Prosperini, Samuele Notarbartolo, Giuseppe Testa, Gioacchino Natoli   +5 more
openalex   +1 more source

Histone demethylases in the regulation of immunity and inflammation. [PDF]

Cell Death Discov, 2023
Qu L, Yin T, Zhao Y, Lv W, Liu Z, Chen C, Liu K, Shan S, Zhou R, Li X, Dong H.   +10 more
europepmc   +1 more source

Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases [PDF]

, 2007
Sunhwa Hong, Young‐Wook Cho, Li‐Rong Yu, Hong Yu, Timothy D. Veenstra, Kai Ge   +5 more
openalex   +1 more source