Results 141 to 150 of about 60,846 (261)

A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation [PDF]

, 2016
Cheng‐Guo Duan, Xingang Wang, Shaojun Xie, Pan Li, Daisuke Miki, Kai Tang, Chuan‐Chih Hsu, Mingguang Lei, Yingli Zhong, Yueh‐Ju Hou, Zhijuan Wang, Zhengjing Zhang, Satendra K. Mangrauthia, Huawei Xu, Heng Zhang, Brian P. Dilkes, W. Andy Tao, Jian‐Kang Zhu   +17 more
openalex   +1 more source

Domestication‐Selected Promoter Insertion in WRKY17 Increases Cadmium Sensitivity in Apple

Plant Biotechnology Journal, EarlyView.
ABSTRACT With increasing industrialisation and human activities, heavy metal pollution has become a serious environmental concern, particularly cadmium (Cd) contamination. This study reveals significant differences in Cd tolerance between wild apple (Malus spp.) and cultivated apple (Malus domestica).
Chanyu Wang, Tianchao Wang, Tong Zhang, Handong Song, Dongqian Shan, Yixue Bai, Zehui Hu, Jianyu Li, Jie Man, Peiyun Xiao, Changjian Dai, Xin Liu, Fei Shen, Jin Kong, Jianfang Hu, Xiaodong Zheng   +15 more
wiley   +1 more source

Cell-free Embryonic Stem Cell Extract-mediated Derivation of Multi-potent Stem Cells from NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair [PDF]

, 2007
The oocyte-independent generation of multipotent stem cells is one of the goals in regenerative medicine. We report that upon exposure to mouse ES cell (ESC) extracts, reversibly permeabilized NIH3T3 cells undergo de-differentiation followed by stimulus ...
Deepali Ahluwalia, Douglas W. Losordo, Erin Lambers, Evelyn Bord, Gangjian Qin, Hiromichi Hamada, Ilona Goukassian, Johnson Rajasingh, Karen Schlauch, Kenneth M. Rosen, Prasanna Krishnamurthy, Raj Kishore, Tina Thorne, Yan Zhu   +13 more
core   +1 more source

PI3K/AKT/mTOR Signaling Mediates Valproic Acid-Induced Neuronal Differentiation of Neural Stem Cells through Epigenetic Modifications

Stem Cell Reports, 2017
Although valproic acid (VPA), has been shown to induce neuronal differentiation of neural stem cells (NSCs), the underlying mechanisms remain poorly understood. Here we investigated if and how mammalian target of rapamycin (mTOR) signaling is involved in
Xi Zhang, Xiaosong He, Qingqing Li, Xuejian Kong, Zhenri Ou, Le Zhang, Zhuo Gong, Dahong Long, Jianhua Li, Meng Zhang, Weidong Ji, Wenjuan Zhang, Liping Xu, Aiguo Xuan   +13 more
doaj   +1 more source

KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcoma. [PDF]

Theranostics, 2021
Jiang Y, Li F, Gao B, Ma M, Chen M, Wu Y, Zhang W, Sun Y, Liu S, Shen H.   +9 more
europepmc   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

TdIF1-LSD1 Axis Regulates Epithelial-Mesenchymal Transition and Metastasis via Histone Demethylation of E-Cadherin Promoter in Lung Cancer. [PDF]

Int J Mol Sci, 2021
Liu Q, Xiong J, Xu D, Hao N, Zhang Y, Sang Y, Wang Z, Zheng X, Min J, Diao H, Raphael J, Maleki Vareki S, Koropatnick J, Min W.   +13 more
europepmc   +1 more source

The Effects of Epigenetics on Stress Response [PDF]

, 2016
Despite the vast amount of resources at the disposal of humanity today, the intricacies of human biology are often a mystery. The chemical and biological products of the human genome have been well studied and documented, but many of the chemical and ...
Suddarth, Kevin
core   +1 more source

DNA Hypomethylation Is One of the Epigenetic Mechanisms Involved in Salt‐Stress Priming in Soybean Seedlings

Plant, Cell &Environment, EarlyView.
ABSTRACT Salt‐stress priming enhances the tolerance of plants against subsequent exposure to a similar stress. Priming‐induced transcriptomic reprogramming is mediated by multiple epigenetic mechanisms, the best known of which is histone modifications. However, not much is known about other epigenetic responses.
Wai‐Shing Yung, Qianwen Wang, Long‐Yiu Chan, Zhili Wang, Mingkun Huang, Man‐Wah Li, Fuk‐Ling Wong, Hon‐Ming Lam   +7 more
wiley   +1 more source

Regulation of histone arginine methylation/demethylation by methylase and demethylase (Review)

Molecular Medicine Reports, 2019
Histone arginine methylation is a universal post‑translational modification that has been implicated in multiple cellular and sub‑cellular processes, including pre‑mRNA splicing, DNA damage signaling, mRNA translation, cell signaling and cell death.
Zhang, Jing, Jing, Li, Li, Menghan, He, Lingfeng, Guo, Zhigang   +4 more
openaire   +3 more sources