Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant [PDF]
Chromosome Research, 2013 The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease.
A. D. McAinsh +72 more
core +18 more sources
Stage-specific histone modification profiles reveal global transitions in the Xenopus embryonic epigenome. [PDF]
, 2011 Vertebrate embryos are derived from a transitory pool of pluripotent cells. By the process of embryonic induction, these precursor cells are assigned to specific fates and differentiation programs.
Arteaga-Salas, Jose M. +6 more
core +10 more sources
The Histone Deacetylase Complex (HDC) 1 protein of Arabidopsis thaliana has the capacity to interact with multiple proteins including histone 3-binding proteins and histone 1 variants [PDF]
, 2016 Intrinsically disordered proteins can adopt multiple conformations thereby enabling interaction with a wide variety of partners. They often serve as hubs in protein interaction networks. We have previously shown that the Histone Deacetylase Complex (HDC)
Amtmann, Anna +6 more
core +1 more source
The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation [PDF]
, 2011 Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant ...
Bowman, A. +6 more
core +4 more sources
Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy. [PDF]
, 2013 Calcium/calmodulin-dependent protein kinase II (CaMKII) plays a central role in pathological cardiac hypertrophy, but the mechanisms by which it modulates gene activity in the nucleus to mediate hypertrophic signaling remain unclear. Here, we report that
An, Woojin +7 more
core +1 more source
Probing the (H3-H4)(2) histone tetramer structure using pulsed EPR spectroscopy combined with site-directed spin labelling [PDF]
, 2009 The (H3-H4)2 histone tetramer forms the central core of nucleosomes and, as such, plays a prominent role in assembly, disassembly and positioning of nucleosomes.
Bowman, A. +4 more
core +4 more sources
New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma [PDF]
, 2008 The anti-epileptic drug valproic acid is also under trial as an anti-cancer agent due to its histone deacetylase (HDAC) inhibitory properties. However, the effects of valproic acid (VPA) are limited and concentrations required for exerting anti ...
Atmaca, Akin +8 more
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Tissue-specific expression of histone H3 variants diversified after species separation [PDF]
, 2015 Additional file 3: Predicted CDS of human histone H3/H4 variants, contains Table S2, which lists the CDS locus information of the predicted human histone H3 and H4 variants in an Excel ...
Akihito Harada +6 more
core +4 more sources
Histone H3 globular domain acetylation identifies a new class of enhancers [PDF]
, 2016 Histone acetylation is generally associated with active chromatin, but most studies have focused on the acetylation of histone tails. Various histone H3 and H4 tail acetylations mark the promoters of active genes.
A Rada-Iglesias +51 more
core +5 more sources
Identification of some heat-induced genes of Trichinella spiralis [PDF]
, 2001 Three heat-induced genes of the infective-stage larvae of Trichinella spiralis were successfully identified by the suppression subtractive hybridization (SSH) technique.
Ko, RCC, Mak, ASC, Sun, KW
core +1 more source