Results 211 to 220 of about 181,554 (237)

Metabolic Diversity of a Widely Distributed Tropical Freshwater Crab Is Not Underpinned by Genetic Differences

open access: yesJournal of Biogeography, EarlyView.
ABSTRACT Aim The aim of this study was to understand the interplay between local and regional factors as drivers of population physiological diversity in a tropical freshwater crab species. Location Western Ghats, south‐west India. Taxon Barytelphusa cunicularis, Brachyura, Crustacea.
Lucy M. Turner   +8 more
wiley   +1 more source

Atrial Fibrillation (AF) and Heart Failure With Preserved Ejection Fraction (HFpEF): Advances and Challenges

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT This state‐of‐the‐art review is based on the Philippe Coumel Lecture in 2024 (Figure 1). It highlights the confluence of two major cardiovascular epidemics, atrial fibrillation and heart failure, with preserved ejection fraction. In these conditions, advances in electrophysiology and heart failure physiology are intertwined and are integrated ...
Sanjeev Saksena   +3 more
wiley   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu   +3 more
wiley   +1 more source

ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT. [PDF]

open access: yesActa Pharm Sin B
Dong M   +16 more
europepmc   +1 more source

Gravitropic Gene Expression Divergence Associated With Adaptation to Contrasting Environments in an Australian Wildflower

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Plants adapt to their local environment through complex interactions between genes, gene networks and hormones. Although the impact of gene expression on trait regulation and evolution has been recognised for many decades, its role in the evolution of adaptation is still a subject of intense exploration.
Zoe Broad   +7 more
wiley   +1 more source

The Roles of Plasticity and Selection in Rapid Phenotypic Changes at the Pacific Oyster Invasion Front in Europe

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Invasive species present significant management challenges worldwide due to their ability to rapidly adapt to novel environments. The Pacific oyster Crassostrea gigas, a globally distributed invasive species, arrived in western Sweden in 2006 but has not yet colonised the low salinity waters of the Baltic Sea, presumably because low salinities
Alexandra Kinnby   +5 more
wiley   +1 more source

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