Results 31 to 40 of about 196,399 (287)

Phorbol ester promotes histone H3-Ser10 phosphorylation at the LDL receptor promoter in a protein kinase C-dependent manner

open access: yesJournal of Lipid Research, 2004
Histone modification is emerging as a major regulatory mechanism for modulating gene expression by altering the accessibility of transcription factors to DNA.
Wei Huang   +4 more
doaj   +1 more source

Failure of long-term memory formation in juvenile snails is determined by acetylation status of histone H3 and can be improved by NaB treatment. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Animals' capacities for different forms of learning do not mature simultaneously during ontogenesis but the molecular mechanisms behind the delayed development of specific types of memory are not fully understood.
Alexandra B Danilova   +1 more
doaj   +1 more source

DNA mismatch repair interacts with CAF-1- and ASF1A-H3-H4-dependent histone (H3-H4)2 tetramer deposition. [PDF]

open access: yes, 2016
DNA mismatch repair (MMR) is required for the maintenance of genome stability and protection of humans from several types of cancer. Human MMR occurs in the chromatin environment, but little is known about the interactions between MMR and the chromatin ...
Kadyrov, Farid A   +2 more
core   +2 more sources

Identification of some heat-induced genes of Trichinella spiralis [PDF]

open access: yes, 2001
Three heat-induced genes of the infective-stage larvae of Trichinella spiralis were successfully identified by the suppression subtractive hybridization (SSH) technique.
Ko, RCC, Mak, ASC, Sun, KW
core   +1 more source

Oncogenic Mechanisms of Histone H3 Mutations [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2016
Recurrent missense mutations in histone H3 were recently reported in pediatric gliomas and soft tissue tumors. Strikingly, these mutations only affected a minority of the total cellular H3 proteins and occurred at or near lysine residues at positions 27 and 36 on the amino-terminal tail of H3 that are subject to well-characterized posttranslational ...
Daniel N, Weinberg   +2 more
openaire   +2 more sources

H3–H4 histone chaperones and cancer

open access: yesCurrent Opinion in Genetics & Development, 2022
Histone chaperones are key regulators of chromatin structure and function. Their frequent mis-regulation in various cancers can impact tumor initiation and progression. Here, we focus on H3-H4 histone chaperones to highlight recent studies concerning their roles in several cancers thereby expanding on previous reports illustrating their functions as ...
Ray-Gallet, Dominique   +1 more
openaire   +3 more sources

Identification and Characterization of Switchgrass histone H3 and CENH3 Genes

open access: yesFrontiers in Plant Science, 2016
Switchgrass is one of the most promising energy crops and only recently has been employed for biofuel production. The draft genome of switchgrass was recently released; however, relatively few switchgrass genes have been functionally characterized. CENH3,
Jiamin Miao   +5 more
doaj   +1 more source

Extracellular Histone H3 Induces Pyroptosis During Sepsis and May Act Through NOD2 and VSIG4/NLRP3 Pathways

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Background: Histones could be released from the nucleus when stimulated. Increasing evidence has shown that extracellular histones are associated with a variety of inflammation and diseases.
Chun-xia Shi   +5 more
doaj   +1 more source

Esperanto for histones : CENP-A, not CenH3, is the centromeric histone H3 variant [PDF]

open access: yes, 2013
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease.
A. D. McAinsh   +72 more
core   +9 more sources

Histone H3 Variants in Trichomonas vaginalis [PDF]

open access: yesEukaryotic Cell, 2012
ABSTRACT The parabasalid protist Trichomonas vaginalis is a widespread parasite that affects humans, frequently causing vaginitis in infected women. Trichomonad mitosis is marked by the persistence of the nuclear membrane and the presence of an asymmetric extranuclear spindle with no obvious direct ...
Zuzana, Zubácová   +2 more
openaire   +2 more sources

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