Results 151 to 160 of about 1,862,085 (289)

Analysis of human, murine and avian erythroid differentiation : modification of the proteome and histones

, 2021
Marjorie Leduc
openalex   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, EarlyView.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

The role of histone modifications and transposable elements in the epigenetic regulation of gene dosage after gene duplication [PDF]

Thomas Wolfe, Frédéric J. J. Chain
openalex   +1 more source

Draper‐ATG3 Interaction Positively Regulates Autophagy to Mediate Silk Gland Degradation in Bombyx mori

Advanced Science, EarlyView.
Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou, Yuhan Luo, Yue Jin, Wenhui Jing, Yuxin Huang, Yanting Liang, Yinghui Li, Zhihua Hao, Yusong Xu, Huabing Wang   +9 more
wiley   +1 more source

Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications

, 2009
Catherine A. Musselman, Robyn E. Mansfield, Adam L. Garske, Foteini Davrazou, Ann H. Kwan, Samuel S. Oliver, Heather O’Leary, John M. Denu, Joel P. Mackay, Tatiana G. Kutateladze   +9 more
openalex   +2 more sources

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Histone modifications: Unveiling the epigenetic enigma of degenerative skeletal diseases. [PDF]

J Orthop Translat
Zhang Y, Wang J, Hua D, Fan C, He W, Deng Y, Tang M, Geng D, Wu X, Mao H.   +9 more
europepmc   +1 more source

DHCR7 expression, function and estrogen-induced promoter histone modification changes in chicken granulosa cells of pre-hierarchical follicles

Dandan Li, Qingqing Wei, Li Kang, Yi Sun, Yunliang Jiang   +4 more
openalex   +1 more source

Chemical Approaches To Understand the Language of Histone Modifications

, 2011
Abhinav Dhall, Champak Chatterjee
openalex   +2 more sources