Results 251 to 260 of about 2,172,961 (295)
Some of the next articles are maybe not open access.
Control of histone modifications
Journal of Cellular Biochemistry, 1999A role for histone modifications in transcription processes and the remodeling of chromatin structure has been established. This review highlights the recent advances made in studies on histone acetyltransferases, histone deacetylases, histone kinases, and protein phosphatases, as well as their roles in transcriptional activation and repression ...
J R, Davie, V A, Spencer
openaire +2 more sources
Role of histone modifications in neurogenesis and neurodegenerative disease development.
Ageing Research ReviewsProgressive neuronal dysfunction and death are key features of neurodegenerative diseases; therefore, promoting neurogenesis in neurodegenerative diseases is crucial.
Anqi Zhao +8 more
semanticscholar +1 more source
Histone Modifications and Cancer
2010It is now widely recognized that epigenetic events are important mechanisms underlying cancer development and progression. Epigenetic information in chromatin includes covalent modifications (such as acetylation, methylation, phosphorylation, and ubiquitination) of core nucleosomal proteins (histones).
Carla, Sawan, Zdenko, Herceg
openaire +2 more sources
Histone modifications and their regulatory roles in plant development and environmental memory.
Journal of genetics and genomics = Yi chuan xue bao, 2019Plants grow in dynamic environments where they receive diverse environmental signals. Swift and precise control of gene expression is essential for plants to align their development and metabolism with fluctuating surroundings.
Ting Zhao, Zhenping Zhan, Danhua Jiang
semanticscholar +1 more source
Detecting Histone Modifications in Plants
2014Histone modifications play an essential role in chromatin-associated processes including gene regulation and epigenetic inheritance. It is therefore very important to quantitatively analyze histone modifications at both the single gene and whole genome level.
Song, J., Rutjens, B., Dean, C.
openaire +2 more sources
Histone modifications in development
DevelopmentABSTRACT In eukaryotic cells, the genetic material is organized into chromatin, which consists mainly of DNA, histones and chromatin-associated proteins. An important regulator of chromatin structure and function are histone post-translational modifications, which can shape gene expression patterns and control the epigenetic landscape ...
Yu-Hao Liu, Robert Schneider
openaire +2 more sources
Histone variants and histone modifications: A structural perspective
Biochemistry and Cell Biology, 2001In this review, we briefly analyze the current state of knowledge on histone variants and their posttranslational modifications. We place special emphasis on the description of the structural component(s) defining and determining their functional role. The information available indicates that this histone "variability" may operate at different levels:
J, Ausió +3 more
openaire +2 more sources
Histone Modification Therapy of Cancer
2010The state of modification of histone tails plays an important role in defining the accessibility of DNA for the transcription machinery and other regulatory factors. It has been extensively demonstrated that the posttranslational modifications of the histone tails, as well as modifications within the nucleosome domain, regulate the level of chromatin ...
Chiara, Biancotto +2 more
openaire +2 more sources
Functional consequences of histone modifications
Current Opinion in Genetics & Development, 2003Covalent modifications of the histone proteins have well-known roles in gene expression. Experiments reported during the past year have extended this paradigm to include roles for histone acetylation and phosphorylation in DNA double-strand break repair.
Masayoshi, Iizuka, M Mitchell, Smith
openaire +2 more sources
Histone interactions, histone modifications and chromatin structure
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1978Abstract A subunit structure for chromatin is now well established (Hewish & Burgoyne 1973; Burgoyne, Hewish & Hobbs 1974; Olins & Olins 1973, 1974; Woodcock 1973; Rill & Van Holde 1973; Kornberg 1974; Baldwin, Boseley, Bradbury & Ibel 1975; Oudet, Gross-Bellard & Chambon 1975)* Nuclease digestion of chromatin ...
openaire +2 more sources