Results 331 to 340 of about 2,005,250 (367)

Histone Variants and Histone Modifications in Neurogenesis

Trends in Cell Biology, 2020
During embryonic brain development, neurogenesis requires the orchestration of gene expression to regulate neural stem cell (NSC) fate specification. Epigenetic regulation with specific emphasis on the modes of histone variants and histone post-translational modifications are involved in interactive gene regulation of central nervous system (CNS ...
Mengtian Zhang, Jinyue Zhao, Yuqing Lv, Wenwen Wang, Chao Feng, Wenzheng Zou, Libo Su, Jianwei Jiao   +7 more
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Overview of Histone Modification

2020
Epigenetics is the epi-information beyond the DNA sequence that can be inherited from parents to offspring. From years of studies, people have found that histone modifications, DNA methylation, and RNA-based mechanism are the main means of epigenetic control. In this chapter, we will focus on the general introductions of epigenetics, which is important
Yanjun, Zhang, Zhongxing, Sun, Junqi, Jia, Tianjiao, Du, Nachuan, Zhang, Yin, Tang, Yuan, Fang, Dong, Fang   +7 more
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Control of histone modifications

Journal of Cellular Biochemistry, 1999
A role for histone modifications in transcription processes and the remodeling of chromatin structure has been established. This review highlights the recent advances made in studies on histone acetyltransferases, histone deacetylases, histone kinases, and protein phosphatases, as well as their roles in transcriptional activation and repression ...
J R, Davie, V A, Spencer
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Histone Modifications and Cancer

2010
It is now widely recognized that epigenetic events are important mechanisms underlying cancer development and progression. Epigenetic information in chromatin includes covalent modifications (such as acetylation, methylation, phosphorylation, and ubiquitination) of core nucleosomal proteins (histones).
Carla, Sawan, Zdenko, Herceg
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Detecting Histone Modifications in Plants

2014
Histone modifications play an essential role in chromatin-associated processes including gene regulation and epigenetic inheritance. It is therefore very important to quantitatively analyze histone modifications at both the single gene and whole genome level.
Song, J., Rutjens, B., Dean, C.
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Histone modifications in herpesvirus infections

Biology of the Cell, 2012
AbstractIn eukaryotic cells, gene expression is not only regulated by transcription factors but also by several epigenetic mechanisms including post‐translational modifications of histone proteins. There are numerous histone modifications described to date and methylation, acetylation, ubiquitination and phosphorylation are amongst the best studied. In
Nina, Van Opdenbosch, Herman, Favoreel, Gerlinde R, Van de Walle   +2 more
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Histone interactions, histone modifications and chromatin structure

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1978
A subunit structure for chromatin is now well established (Hewish & Burgoyne 1973; Burgoyne, Hewish & Hobbs 1974; Olins & Olins 1973, 1974; Woodcock 1973; Rill & Van Holde 1973; Kornberg 1974; Baldwin, Boseley, Bradbury & Ibel 1975; Oudet, Gross-Bellard & Chambon 1975)* Nuclease digestion of chromatin gives a series
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Histone modifications and exercise adaptations

Journal of Applied Physiology, 2011
The spatial association between genomic DNA and histone proteins within chromatin plays a key role in the regulation of gene expression and is largely governed by post-translational modifications to histone proteins, particularly H3 and H4. These modifications include phosphorylation, acetylation, and mono-, di-, and tri-methylation, and while some ...
Sean L, McGee, Mark, Hargreaves
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The analysis of histone modifications

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2006
The biological function of many proteins is often regulated through posttranslational modifications (PTMs). Frequently different modifications influence each other and lead to an intricate network of interdependent modification patterns that affect protein-protein interactions, enzymatic activities and sub-cellular localizations.
Ana, Villar-Garea, Axel, Imhof
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Histone post-translational modifications — cause and consequence of genome function

Nature reviews genetics, 2022
Gonzalo Millán-Zambrano, Adam Burton, Andrew J. Bannister, Robert Schneider   +3 more
semanticscholar   +1 more source