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Histone variants in skeletal myogenesis [PDF]
Epigenetics, 2021 Histone variants regulate chromatin accessibility and gene transcription. Given their distinct properties and functions, histone varint substitutions allow for profound alteration of nucleosomal architecture and local chromatin landscape.
Nandini Karthik, Reshma Taneja
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Histone variants shape chromatin states in Arabidopsis [PDF]
eLife, 2023 How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone ...
Bhagyshree Jamge +8 more
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Advances in biological functions and mechanisms of histone variants in plants [PDF]
Frontiers in Genetics, 2023 Nucleosome is the basic subunit of chromatin, consisting of approximately 147bp DNA wrapped around a histone octamer, containing two copies of H2A, H2B, H3 and H4.
Xi Wu +4 more
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The Function of H2A Histone Variants and Their Roles in Diseases [PDF]
BiomoleculesEpigenetic regulation, which is characterized by reversible and heritable genetic alterations without changing DNA sequences, has recently been increasingly studied in diseases.
Xuemin Yin +4 more
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Contribution of histone variants to aneuploidy: a cancer perspective [PDF]
Frontiers in Genetics, 2023 Histone variants, which generally differ in few amino acid residues, can replace core histones (H1, H2A, H2B, and H3) to confer specific structural and functional features to regulate cellular functions.
Denise Ragusa, Paola Vagnarelli
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Histone Variants: Guardians of Genome Integrity [PDF]
Cells, 2020 Chromatin integrity is key for cell homeostasis and for preventing pathological development. Alterations in core chromatin components, histone proteins, recently came into the spotlight through the discovery of their driving role in cancer.
Juliette Ferrand +2 more
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Proteomic Analysis of Histone Variants and Their PTMs: Strategies and Pitfalls [PDF]
Proteomes, 2018 Epigenetic modifications contribute to the determination of cell fate and differentiation. The molecular mechanisms underlying histone variants and post-translational modifications (PTMs) have been studied in the contexts of development, differentiation,
Sara El Kennani +3 more
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Histone Variants and Their Chaperones in Hematological Malignancies [PDF]
HemaSphere, 2023 Epigenetic regulation occurs on the level of compacting DNA into chromatin. The functional unit of chromatin is the nucleosome, which consists of DNA wrapped around a core of histone proteins.
Ecem Kirkiz +3 more
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Histone Variants in the Specialization of Plant Chromatin. [PDF]
Annu Rev Plant Biol, 2022 The basic unit of chromatin, the nucleosome, is an octamer of four core histone proteins (H2A, H2B, H3, and H4) and serves as a fundamental regulatory unit in all DNA-templated processes.
Foroozani M, Holder DH, Deal RB.
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Histone variants and modifications during abiotic stress response. [PDF]
Front Plant Sci, 2022 Plants have developed multiple mechanisms as an adaptive response to abiotic stresses, such as salinity, drought, heat, cold, and oxidative stress. Understanding these regulatory networks is critical for coping with the negative impact of abiotic stress ...
Nunez-Vazquez R +2 more
europepmc +2 more sources