Results 251 to 260 of about 394,873 (373)

A phase I trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenously administered low-anticoagulant heparin (M6229) in critically ill sepsis patients. [PDF]

open access: yesIntensive Care Med Exp
van Mourik N   +14 more
europepmc   +1 more source

Role of extracellular histones in the cardiomyopathy of sepsis

open access: yesThe FASEB Journal, 2015
M. Kalbitz   +15 more
semanticscholar   +1 more source

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

open access: yesAdvanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin   +11 more
wiley   +1 more source

Chemical Studies of Histone Methylation

open access: hybrid, 1969
Edward L. Gershey   +3 more
openalex   +1 more source

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones

open access: yesNature Structural &Molecular Biology, 2014
T. Kanno   +12 more
semanticscholar   +1 more source

Gene Editing of a Susceptibility LncRNA Enhances Broad‐Spectrum Disease Resistance in Rice without Developmental Trade‐Offs

open access: yesAdvanced Science, EarlyView.
Editing susceptibility lncRNAs offers a strategy to enhance disease resistance without yield loss. RESIS, a domestication‐acquired, pathogen‐induced lncRNA, promotes protein N‐terminal acetylation through its interaction with NatA complex. Knockout of RESIS increases translation and confers broad‐spectrum resistance to both fungal and bacterial ...
Wen‐long Zhao   +17 more
wiley   +1 more source

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