Results 41 to 50 of about 67,934 (145)
Molecular Cancer, 2023 Background Colorectal cancer liver metastases (CRCLM) are associated with a poor prognosis, reflected by a five-year survival rate of 14%. Anti-angiogenic therapy through anti-VEGF antibody administration is one of the limited therapies available ...
Johannes Robert Fleischer +17 more
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Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice. [PDF]
PLoS ONE, 2016 Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) into tumors.
Hanneke Korsten +5 more
doaj +1 more source
Heliyon, 2022 Histological changes in tissue are of primary importance in pathological research and diagnosis. Automated histological analysis requires ability to computationally separate pathological alterations from normal tissue.
Pekka Ruusuvuori +6 more
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Diagnostic Pathology, 2021 Background Thyroid tumors are often difficult to histopathologically diagnose, particularly follicular adenoma (FA) and follicular carcinoma (FC). Papillary carcinoma (PAC) has several histological subtypes.
Kimihide Kusafuka +9 more
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The challenges and pitfalls of diagnosing adenomyoepithelioma in needle core biopsies of the breast
Human Pathology Reports, 2021 Adenomyoepithelioma (AME) is a rare mammary neoplasm characterized by a biphasic proliferation of both myoepithelial and epithelial cells. These two cellular populations can contribute disproportionately to the lesion and assume a wide spectrum of growth
Ingrid S. Tam, Karan Vats, Chunjie Wang
doaj +1 more source
Histopathological growth pattern and vessel co-option in intrahepatic cholangiocarcinoma
Medical Molecular MorphologyAbstractIntrahepatic cholangiocarcinoma (iCCA) exhibits different blood imaging features and prognosis depending on histology. To clarity histopathological growth patterns (HGPs) and vascularization processes of iCCA, we collected 145 surgical specimens and histologically classified them into large bile duct (LBD) (20 cases), small bile duct (SBD) (54),
Zihan Li +14 more
+5 more sources
Immune phenotype and histopathological growth pattern in patients with colorectal liver metastases
British Journal of Cancer, 2020 Abstract Background Patients with desmoplastic (angiogenic) histopathological growth pattern (HGP) colorectal liver metastases (CLM) might derive more benefit from bevacizumab-based chemotherapy than those with replacement (non-angiogenic) HGP. This study investigated the association of HGP with the immune phenotype (IP)
Stefan Stremitzer +11 more
openaire +2 more sources
World Journal of Gastroenterology, 2022 Liver is the most common site of metastases of colorectal cancer, and liver metastases present with distinct histopathological growth patterns (HGPs), including desmoplastic, pushing and replacement HGPs and two rare HGPs. HGP is a miniature of tumor-host reaction and reflects tumor biology and pathological features as well as host immune dynamics ...
Kong, Bing-Tan +4 more
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Cultivation of retinoblastoma cells: Correlation between in vitro growth pattern and histopathology
Journal of Ophthalmic and Vision Research, 2016 To investigate the correlation between floating versus adherent growth pattern of cultivated retinoblastoma (RB) cells from three patients with RB and their histopathologic features.RB cells from three Iranian patients (MM, NR, and MS) were cultivated in Dulbecco's modified eagle medium (DMEM) supplemented with 15% fetal bovine serum (FBS) for four ...
Narges Fazili +4 more
openaire +3 more sources
, 2021 We retrospectively investigated histopathological growth patterns in individuals with advanced nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) treated within the randomized HD18 study.
Andreas Engert +31 more
core +1 more source