Results 1 to 10 of about 68,793 (99)

Long non-coding RNAs CCAT1 and CCAT2 in colorectal liver metastases are tumor-suppressive via MYC interaction and might predict patient outcomes.

PLoS ONE, 2023
BackgroundLiver metastases severely reduce the long term survival of colorectal cancer patients. Long non-coding RNAs (lncRNAs) CCAT1 and CCAT2 have previously been found to be associated with impaired patient outcomes in primary colorectal cancer.
Clemens Franz, Michael Wuehrl, Sibylle Hartmann, Fee Klupp, Thomas Schmidt, Martin Schneider   +5 more
doaj   +3 more sources

RETRACTED: Open Resection Compared to Mini-Invasive in Colorectal Cancer and Liver Metastases: A Meta-Analysis

Frontiers in Surgery, 2021
Background: We performed a meta-analysis to evaluate the outcomes of minimally invasive surgery and open surgery in the simultaneous resection of colorectal cancer and synchronous colorectal liver metastases.Methods: A systematic literature search up to ...
Jie Gong, Fengwei Gao, Qingyun Xie, Xin Zhao, Zehua Lei   +4 more
doaj   +1 more source

Protective effect of miR‐18a in resected liver metastases of colorectal cancer and FOLFOX treatment

Cancer Reports, 2023
Background Colorectal cancer ranks second in terms of cancer associated deaths worldwide, whereas miRNA play a pivotal role in the etiology of cancer and its metastases.
Clemens Franz, Laila Jötten, Michael Wührl, Sibylle Hartmann, Fee Klupp, Thomas Schmidt, Martin Schneider   +6 more
doaj   +1 more source

Current trends and outcomes of surgical treatment of colorectal cancer with liver metastasis

Сибирский онкологический журнал, 2022
Aim. To analyze multimodal treatment outcomes in patients with liver metastases from colorectal cancer, who were treated at multidisciplinary cancer clinic. Material and methods.
A. V. Shabunin, V. V. Bedin, D. N. Grekov, M. M. Tavobilov, P. A. Drozdov, S. S. Lebedev, A. A. Karpov, G. M. Chechenin, V. A. Tsurkan   +8 more
doaj   +1 more source

Complete remission of multiple liver metastases with only partial response of the primary rectal cancer after neoadjuvant chemotherapy

Surgical Case Reports, 2020
Background Colorectal cancer is commonly diagnosed among the Japanese population, and various strategies in treating the colorectal liver metastasis have been introduced over the years.
Satomi Miura, Kyoji Ito, Nobuyuki Takemura, Fuminori Mihara, Tomomichi Kiyomatsu, Norihiro Kokudo   +5 more
doaj   +1 more source

Two cases of colorectal liver metastasis with residual liver recurrence after a long recurrence-free survival period

Surgical Case Reports, 2023
Background The rate of residual liver recurrence after the resection of colorectal liver metastases is high, and most cases recur within 5 years of the initial hepatectomy. Here, we report two cases of residual liver recurrence after radical resection of
Shotaro Yagi, Makoto Takahashi, Taiki Tsuji, Susumu Yanagibashi, Taku Higashihara, Hideo Ohtsuka, Tatsuya Hayashi, Kunio Takuma, Yasuhiro Morita, Ayano Nakazono, Haruka Okada, Masayuki Ohtsuka   +11 more
doaj   +1 more source

The predictive value of liver tests for the presence of liver metastases

Hepatic Oncology, 2023
Aim: To analyze the predictive value of biochemical liver tests in patients with malignant melanoma, breast, colorectal or lung cancers at the time of diagnosis of liver metastases.
Alexandra V Kimchy, Harjit Singh, Esha Parikh, Jessica Rosenberg, Kavya Sanghavi, James H Lewis   +5 more
doaj   +1 more source

A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy

npj Precision Oncology, 2022
Personalized treatment approaches for patients with limited liver metastases from colorectal cancer are critically needed. By leveraging three large, independent cohorts of patients with colorectal liver metastases (n = 336), we found that a ...
Liam F. Spurr, Carlos A. Martinez, Rohan R. Katipally, Soumya C. Iyer, Sian A. Pugh, John A. Bridgewater, John N. Primrose, Enric Domingo, Timothy S. Maughan, Michael I. D’Angelica, Mark Talamonti, Mitchell C. Posner, Philip P. Connell, Ralph R. Weichselbaum, Sean P. Pitroda   +14 more
doaj   +1 more source

A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer

Trials, 2023
Introduction Fifteen to 25% of patients with colorectal cancer have combined liver metastases at the time of diagnosis, whereas an additional 15 to 25% will develop liver metastases after curative resection of primary colorectal cancer, with the vast ...
Rui Qi Gao, Zhen Chang Mo, Hai Kun Zhou, Peng Fei Yu, Wei Dong Wang, Dan Hong Dong, Xi Sheng Yang, Xiao Hua Li, Gang Ji   +8 more
doaj   +1 more source

MiRNA-21 Expression Decreases from Primary Tumors to Liver Metastases in Colorectal Carcinoma. [PDF]

PLoS ONE, 2016
OBJECTIVE:Metastasis is the major cause of death in colorectal cancer patients. Expression of certain miRNAs in the primary tumors has been shown to be associated with progression of colorectal cancer and the initiation of metastasis.
Fabian Feiersinger, Elke Nolte, Sven Wach, Tilman T Rau, Nikolaos Vassos, Carol Geppert, Andreas Konrad, Susanne Merkel, Helge Taubert, Michael Stürzl, Roland S Croner   +10 more
doaj   +1 more source