Results 21 to 30 of about 4,157,974 (295)

MiRNA-21 Expression Decreases from Primary Tumors to Liver Metastases in Colorectal Carcinoma. [PDF]

open access: yesPLoS ONE, 2016
OBJECTIVE:Metastasis is the major cause of death in colorectal cancer patients. Expression of certain miRNAs in the primary tumors has been shown to be associated with progression of colorectal cancer and the initiation of metastasis.
Fabian Feiersinger   +10 more
doaj   +1 more source

Macrophages in Colorectal Cancer Liver Metastases

open access: yesCancers, 2019
Tumor-associated macrophages (TAMs) provide a nurturing microenvironment for metastasis and are concomitantly key determinants of the efficacy of anticancer strategies. TAM represent an extremely heterogeneous population in terms of cell morphology, functions, and tissue localization.
Cortese N.   +6 more
openaire   +3 more sources

Can localised 19F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response? [PDF]

open access: yes, 2010
Background 5-Fluorouracil remains widely used in colorectal cancer treatment more than 40 years after its development. 19F magnetic resonance spectroscopy can be used in vivo to measure 5FU’s half-life and metabolism to cytotoxic fluoronucleotides ...
Griffiths, John R.   +17 more
core   +1 more source

Liver transplantation for unresectable hepatic metastases from colorectal cancer: literature review [PDF]

open access: yesArchives of the Balkan Medical Union, 2019
Colorectal cancer represents one of the most common malignancies reported worldwide, associated with an increased risk of hepatic metastases development.
Nicolae BACALBASA   +3 more
doaj   +1 more source

Treatment of liver metastases of colorectal cancer

open access: yesAnnals of Oncology, 2005
Colorectal cancer is one of the most common malignancies,with 1 million new cases and half a million deaths eachyear worldwide [1]. The development of metastases is themain cause of death. Liver metastases are diagnosed in10–25% of patients at the time of resection of their primarycolorectal tumor and, eventually, up to 70% of patients withcolorectal ...
J, Rothbarth, C J H, van de Velde
openaire   +2 more sources

Evidence for Two Modes of Synergistic Induction of Apoptosis by Mapatumumab and Oxaliplatin in Combination with Hyperthermia in Human Colon Cancer Cells [PDF]

open access: yes, 2013
Colorectal cancer is the third leading cause of cancer-related mortality in the world-- the main cause of death from colorectal cancer is hepatic metastases, which can be treated with isolated hepatic perfusion (IHP).
Yong J. Lee   +16 more
core   +2 more sources

The comparative analysis of immunohistochemical parameters of primary liver cancer and liver metastases of malignant tumors of solid, trabecular, tubular-glandular structure in puncture trephine biopsy

open access: yesPatologìâ, 2015
Aim. In puncture trephine biopsy of the liver differential immunohistochemical (IHC) parameters of hepatocellular carcinoma (HCC) in 30 patients, cholangiocellular cancer (CC) of the liver in 15 patients, and liver metastases of malignant tumors of solid,
V. A. Tumanskiy   +2 more
doaj   +1 more source

Prognosis-related Factors of Colorectal Cancer Patients with Positive PD-L1 Expression in Liver Metastases After Hepatectomy

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To evaluate the prognosis-related factors of colorectal cancer patients with positive PD-L1 expression in liver metastases after hepatectomy. Methods We reviewed retrospectively the clinical data of 68 colorectal cancer patients with positive ...
ZHAO Zhengqiang   +3 more
doaj   +1 more source

Liver metastases in patients with curatively treated colorectal cancer

open access: yesСибирский онкологический журнал, 2019
Background. The problem of the development of liver metastases in colorectal cancer patients previously treated with curative intent surgery remains little studied. Identification of significant factors affecting the occurrence of metachronous metastasis
R. I. Rasulov   +2 more
doaj   +1 more source

Multi-Omics Analysis of the Tumor Microenvironment in Liver Metastasis of Colorectal Cancer Identified FJX1 as a Novel Biomarker

open access: yesFrontiers in Genetics, 2022
Colorectal cancer incidence and mortality have increased in recent years, with more than half of patients who died of colorectal cancer developing liver metastases.
Junwei Zou   +7 more
doaj   +1 more source

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