Results 31 to 40 of about 68,962 (266)

LIVER RESECTION FOR METASTASES FROM COLORECTAL CANCER [PDF]

Medical Journal Armed Forces India, 1999
Five percent of patients with liver secondaries from colorectal carcinoma are potentially resectable and several studies have demonstrated significantly improved survival following resection. Two hundred and ten patients operated for colorectal carcinoma were followed up.
H G, Mukhopadhyay, L S, Vohra, A K, Sharma, R, Solanki, P S, Reddy, G S, Chopra, P, Subhas   +6 more
openaire   +2 more sources

Hepatic resection for primary and secondary liver malignancies

Innovative Surgical Sciences, 2017
Liver surgery has become the standard treatment of primary liver cancer and liver metastases from colorectal cancer. Also, patients with non-colorectal liver metastases are increasingly offered surgery due to the low morbidity and excellent long-term ...
Heinrich Stefan, Lang Hauke
doaj   +1 more source

Use of cytoceratin-20 in revealing of colorectal cancer metastases in liver [PDF]

Саратовский научно-медицинский журнал, 2013
The aim of the study is to evaluate the possibilities of immunohistochemical revealing of colorectal cancer micro-metastases in liver and to determine their prognostic significance. Material et metods.
Fedorina Т.A., Yugina 0.V., Vozdvijenski M.0.   +2 more
doaj  

De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity

Genome Medicine, 2021
Background Gene expression-based subtyping has the potential to form a new paradigm for stratified treatment of colorectal cancer. However, current frameworks are based on the transcriptomic profiles of primary tumors, and metastatic heterogeneity is a ...
Seyed H. Moosavi, Peter W. Eide, Ina A. Eilertsen, Tuva H. Brunsell, Kaja C. G. Berg, Bård I. Røsok, Kristoffer W. Brudvik, Bjørn A. Bjørnbeth, Marianne G. Guren, Arild Nesbakken, Ragnhild A. Lothe, Anita Sveen   +11 more
doaj   +1 more source

Liver transplantation for colorectal cancer with liver metastases

The Oncologist
Abstract Over the last decade, multiple clinical trials have demonstrated a survival benefit for liver transplantation in colorectal cancer with liver metastases. Additionally, advances in donor organ preservation have expanded organ availability affording the opportunity to expand indications for liver transplantation, such as ...
Benjamin E Ueberroth, Michael Kriss, James R Burton, Wells A Messersmith   +3 more
openaire   +2 more sources

Case report: hepatic arterial infusion chemotherapy combined with sintilimab and lenvatinib for conversion therapy of colorectal cancer liver metastases

Frontiers in Immunology, 2023
BackgroundLiver metastasis is one of the most common causes of death in patients with colorectal cancer. Therefore, improving the treatment effect of liver metastatic carcinoma of colorectal cancer is also one of the effective ways to improve the ...
Kai Peng, Yuhua Li, Hao Su, Chenlu Lan, Zaida Huang, Yongguang Wei, Xiwen Liao, Xiwen Liao, Minhao Peng, Tao Peng, Tao Peng, Tao Peng, Guangzhi Zhu, Guangzhi Zhu   +13 more
doaj   +1 more source

Managing Synchronous Liver Metastases in Colorectal Cancer [PDF]

Indian Journal of Surgical Oncology, 2018
The most common site of blood-borne metastases from colorectal cancers (CRC) is the liver. Resection of (liver) metastases is a part of standard treatment of metastatic colorectal cancer. Hepatic resection is the first-line treatment of liver metastases, with 5-year survival rates between 25 and 58%.
ÇETİN, BÜLENT, BİLGETEKİN, İREM, ÖZET, AHMET, CENGİZ, MUSTAFA   +3 more
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Liver Metastases in Colorectal Cancer

Journal of the Korean Society of Coloproctology, 2009
Liver metastases in colorectal cancer are a frequent and lethal complication. Although hepatic resection is an effective treatment for patients with liver metastases in colorectal cancer, only 10-20% of the patients with liver metastases in colorectal cancer are indicated on hepatic resection. However, over the past several decades, liver resection has
Jae Im Lee, Seong Taek Oh
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source