Results 11 to 20 of about 68,962 (266)

Updates of colorectal cancer liver metastases therapy: review on DEBIRI

Hepatic Oncology, 2020
Colorectal cancer is a worldwide public health issue, presenting an advanced stage at diagnosis in more than 20% of patients. Liver metastases are the most common metastatic sites and are not indicated for resection in 80% of cases.
Giammaria Fiorentini, Donatella Sarti, Roberto Nani, Camillo Aliberti, Caterina Fiorentini, Stefano Guadagni   +5 more
doaj   +3 more sources

Colorectal Cancer, Liver Metastases and Biotherapies [PDF]

Biomedicines, 2021
(1) Background: colorectal cancer (CRC) is one of the deadliest causes of death by cancer worldwide. Its first main metastatic diffusion spreads to the liver. Different mechanisms such as the epithelial–mesenchymal transition and angiogenesis are the characteristics of this invasion.
Daniel-Clement Osei-Bordom, Sivesh Kamarajah, Niki Christou   +2 more
openaire   +3 more sources

Radiomics and Radiogenomics in Evaluation of Colorectal Cancer Liver Metastasis

Frontiers in Oncology, 2022
Colorectal cancer is one common digestive malignancy, and the most common approach of blood metastasis of colorectal cancer is through the portal vein system to the liver.
Yun Wang, Lu-Yao Ma, Xiao-Ping Yin, Bu-Lang Gao   +3 more
doaj   +1 more source

Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

BMC Gastroenterology, 2008
Background The tumour suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. To evaluate the correlation between PTEN expression and clinicopathological characteristics of colorectal cancer ...
Funahashi Hitoshi, Takahashi Hiroki, Wakasugi Takehiro, Matsuo Yoichi, Ma Jiachi, Ochi Nobuo, Yasuda Akira, Sawai Hirozumi, Sato Mikinori, Takeyama Hiromitsu   +9 more
doaj   +1 more source

Liver transplantation for unresectable hepatic metastases from colorectal cancer: literature review [PDF]

Archives of the Balkan Medical Union, 2019
Colorectal cancer represents one of the most common malignancies reported worldwide, associated with an increased risk of hepatic metastases development.
Nicolae BACALBASA, Irina BALESCU, Mihaela VILCU, Iulian BREZEAN   +3 more
doaj   +1 more source

Macrophages in Colorectal Cancer Liver Metastases

Cancers, 2019
Tumor-associated macrophages (TAMs) provide a nurturing microenvironment for metastasis and are concomitantly key determinants of the efficacy of anticancer strategies. TAM represent an extremely heterogeneous population in terms of cell morphology, functions, and tissue localization.
Cortese N., Soldani C., Franceschini B., Barbagallo M., Marchesi F., Torzilli G., Donadon M.   +6 more
openaire   +3 more sources

The comparative analysis of immunohistochemical parameters of primary liver cancer and liver metastases of malignant tumors of solid, trabecular, tubular-glandular structure in puncture trephine biopsy

Patologìâ, 2015
Aim. In puncture trephine biopsy of the liver differential immunohistochemical (IHC) parameters of hepatocellular carcinoma (HCC) in 30 patients, cholangiocellular cancer (CC) of the liver in 15 patients, and liver metastases of malignant tumors of solid,
V. A. Tumanskiy, M. D. Zubko, V. G. Maksimenko   +2 more
doaj   +1 more source

Prognosis-related Factors of Colorectal Cancer Patients with Positive PD-L1 Expression in Liver Metastases After Hepatectomy

Zhongliu Fangzhi Yanjiu, 2021
Objective To evaluate the prognosis-related factors of colorectal cancer patients with positive PD-L1 expression in liver metastases after hepatectomy. Methods We reviewed retrospectively the clinical data of 68 colorectal cancer patients with positive ...
ZHAO Zhengqiang, CHEN Long, LIU Yujie, TIAN Suqing   +3 more
doaj   +1 more source

Multi-Omics Analysis of the Tumor Microenvironment in Liver Metastasis of Colorectal Cancer Identified FJX1 as a Novel Biomarker

Frontiers in Genetics, 2022
Colorectal cancer incidence and mortality have increased in recent years, with more than half of patients who died of colorectal cancer developing liver metastases.
Junwei Zou, Hesong Zhang, Yong Huang, Wenjing Xu, Yujin Huang, Siyuan Zuo, Zhenhan Li, Hailang Zhou   +7 more
doaj   +1 more source

X-ray-endovascular interventions in the treatment of patients with liver metastases of colorectal cancer after the termination of systemic chemotherapy [PDF]

Клиническая практика, 2022
Background: At present, the problem of treating common forms of colorectal cancer does not lose its relevance due to the increase in its incidence.
Oksana Yu. Stukalova, Aleksey A. Polikarpov, Roman V. Ishchenko, Zaurbek Kh. Shugushev   +3 more
doaj   +1 more source