Results 21 to 30 of about 8,202,239 (241)

Classifying histopathological growth patterns for resected colorectal liver metastasis with a deep learning analysis. [PDF]

BJS Open
BACKGROUND: Histopathological growth patterns are one of the strongest prognostic factors in patients with resected colorectal liver metastases. Development of an efficient, objective and ideally automated histopathological growth pattern scoring method ...
Höppener DJ, Aswolinskiy W, Qian Z, Tellez D, Nierop PMH, Starmans M, Nagtegaal ID, Doukas M, de Wilt JHW, Grünhagen DJ, van der Laak JAWM, Vermeulen P, Ciompi F, Verhoef C.   +13 more
europepmc   +4 more sources

Histopathological growth patterns as biomarker for adjuvant systemic chemotherapy in patients with resected colorectal liver metastases. [PDF]

Clin Exp Metastasis, 2020
Buisman FE, van der Stok EP, Galjart B, Vermeulen PB, Balachandran VP, Coebergh van den Braak RRJ, Creasy JM, Höppener DJ, Jarnagin WR, Kingham TP, Nierop PMH, Sadot E, Shia J, Groot Koerkamp B, Grünhagen DJ, D'Angelica M, Verhoef C.   +16 more
europepmc   +2 more sources

Different Forms of Tumor Vascularization and Their Clinical Implications Focusing on Vessel Co-option in Colorectal Cancer Liver Metastases

Frontiers in Cell and Developmental Biology, 2021
In modern anti-cancer therapy of metastatic colorectal cancer (mCRC) the anti-angiogenic treatment targeting sprouting angiogenesis is firmly established for more than a decade. However, its clinical benefits still remain limited. As liver metastases (LM)
Gwendolyn Haas, Shuang Fan, Michael Ghadimi, Tiago De Oliveira, Lena-Christin Conradi   +4 more
doaj   +1 more source

Replacement and desmoplastic histopathological growth patterns: A pilot study of prediction of outcome in patients with uveal melanoma liver metastases. [PDF]

J Pathol Clin Res, 2018
Barnhill R, Vermeulen P, Daelemans S, van Dam PJ, Roman-Roman S, Servois V, Hurbain I, Gardrat S, Raposa G, Nicolas A, Dendale R, Pierron G, Desjardins L, Cassoux N, Piperno-Neumann S, Mariani P, Lugassy C.   +16 more
europepmc   +2 more sources

Histopathological Growth Patterns and Survival After Resection of Colorectal Liver Metastasis: An External Validation Study. [PDF]

JNCI Cancer Spectr, 2021
Abstract Background After resection of colorectal cancer liver metastases (CRLM), 2 main histopathological growth patterns can be observed: a desmoplastic and a nondesmoplastic subtype. The desmoplastic subtype has been associated with superior survival. These findings require external validation.
Höppener DJ, Galjart B, Nierop PMH, Buisman FE, van der Stok EP, Coebergh van den Braak RRJ, van Amerongen MJ, Balachandran VP, Jarnagin WR, Kingham TP, Doukas M, Shia J, Nagtegaal ID, Vermeulen PB, Koerkamp BG, Grünhagen DJ, de Wilt JHW, D'Angelica MI, Verhoef C.   +18 more
europepmc   +7 more sources

A Comprehensive Prognostic Model for Colorectal Cancer Liver Metastasis Recurrence After Neoadjuvant Chemotherapy

Frontiers in Oncology, 2022
BackgroundFor patients with colorectal cancer liver metastases (CRLMs), it is important to stratify patients according to the risk of recurrence. This study aimed to validate the predictive value of some clinical, imaging, and pathology biomarkers and ...
Zhenyuan Zhou, Xin Han, Diandian Sun, Zhiying Liang, Wei Wu, Haixing Ju   +5 more
doaj   +1 more source

LAD-GCN: Automatic diagnostic framework for quantitative estimation of growth patterns during clinical evaluation of lung adenocarcinoma

Frontiers in Physiology, 2022
Quantitative estimation of growth patterns is important for diagnosis of lung adenocarcinoma and prediction of prognosis. However, the growth patterns of lung adenocarcinoma tissue are very dependent on the spatial organization of cells.
Wei Xiao, Yanyun Jiang, Zhigang Yao, Xiaoming Zhou, Xiaodan Sui, Yuanjie Zheng   +5 more
doaj   +1 more source

Growth Patterns of Pituitary Adenomas and Histopathological Correlates [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2014
The factors associated with pituitary adenoma (PA) growth rate remain unclear.The objective of the study was to establish whether the preoperative growth and extension pattern of PA can predict postoperative growth rate and recurrence in addition to whether the PA growth rate correlates with proliferation and growth factor expression.One hundred fifty ...
Eric, Monsalves, Soroush, Larjani, Bruno, Loyola Godoy, Kyle, Juraschka, Felipe, Carvalho, Walter, Kucharczyk, Abhaya, Kulkarni, Ozgur, Mete, Fred, Gentili, Shereen, Ezzat, Gelareh, Zadeh   +10 more
openaire   +2 more sources

Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases. [PDF]

Clin Exp Metastasis, 2023
Abstract Metastatic breast cancer (mBC) remains incurable and liver metastases (LM) are observed in approximately 50% of all patients with mBC. In some cases, surgical resection of breast cancer liver metastases (BCLM) is associated with prolonged survival.
Leduc S, Nguyen HL, Richard F, Zels G, Mahdami A, De Schepper M, Maetens M, Pabba A, Jaekers J, Latacz E, Bohlok A, Vanderheyden E, Van Brussel T, Boeckx B, Schepers R, Lambrechts D, Dirix L, Larsimont D, Vankerckhove S, Lucidi V, Topal B, Bachir I, Donckier V, Floris G, Vermeulen P, Desmedt C.   +25 more
europepmc   +4 more sources

Salvage treatment for recurrences after first resection of colorectal liver metastases: the impact of histopathological growth patterns. [PDF]

Clin Exp Metastasis, 2019
Nierop PMH, Galjart B, Höppener DJ, van der Stok EP, Coebergh van den Braak RRJ, Vermeulen PB, Grünhagen DJ, Verhoef C.   +7 more
europepmc   +2 more sources