Results 11 to 20 of about 8,202,239 (241)

Histopathological growth patterns of neuroendocrine tumor liver metastases. [PDF]

Clin Exp Metastasis, 2023
AbstractHistopathological growth patterns (HGPs) of liver metastases represent a potential biomarker for prognosis after resection. They have never been studied in neuroendocrine tumor liver metastases (NETLM). This study evaluated if distinct HGPs can be observed in resected NETLM and if they have prognostic value.
Meyer Y, Bohlok A, Olthof P, Donckier V, Doukas M, Lucidi V, Vermeulen P, Grünhagen D, Verhoef C.   +8 more
europepmc   +10 more sources

Histopathological Growth Pattern in Colorectal Liver Metastasis and The Tumor Immune Microenvironment [PDF]

Cancers, 2022
Almost half of all patients with colorectal cancer present with or eventually develop metastasis, most frequently in the liver. Understanding the histopathological growth patterns and tumor immune microenvironment of colorectal liver metastases may help determine treatment strategies and assess prognosis.
Claudia Zaharia, Torhild Veen, Dordi Lea, Arezo Kanani, Marina Alexeeva, Kjetil Søreide   +5 more
openaire   +5 more sources

Histopathological growth patterns of primary and secondary malignant liver tumors [PDF]

HGPs are a prognostic and predictive biomarker in patients with malignant liver tumors. They can be classified into desmoplastic HGP (dHGP), replacement HGP (rHGP) and pushing HGP (pHGP). The objective of this thesis was to describe the histopathological growth patterns (HGPs) of primary and secondary malignant liver tumors and to evaluate their ...
Meyer, Yannick
core   +13 more sources

On the histopathological growth patterns of colorectal liver metastasis:a Study of Histology, Immunology, Genetics, and Prognosis [PDF]

, 2022
This thesis aims to validate and establish the histopathological growth patterns of colorectal cancer liver metastasis as a relevant biomarker, and to evaluate immunity and genetics as potential underlying biological ...
Höppener, Diederik
core   +11 more sources

Spatial transcriptomics differences of histopathological growth patterns in colorectal cancer liver metastases. [PDF]

Br J Cancer
Abstract Background Histopathological growth patterns (HGPs) have emerged as prognostic and predictive biomarkers in colorectal liver metastases (CLM). The desmoplastic/encapsulating HGP (EHGP) is associated with improved survival after surgery, whereas the replacement HGP (RHGP) is associated ...
Escriva Conde M, Andersson A, Vermeulen P, Nilsson M, Nyström H.   +4 more
europepmc   +5 more sources

P019: Unfavorable prognostic value of the predominance of THRLBCL-like histopathological growth patterns in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) [PDF]

HemaSphere, 2022
Elena Dorokhina, T.N. Moiseeva, A.M. Kovrigina, Irirna Shupletsova, L.S. Al-Radi, Yu. A. Chabaeva, Ya.K. Mangasarova   +6 more
doaj   +2 more sources

Molecular, histopathological and radiological profiling of the histopathological growth patterns of liver metastases

, 2022
Abstract: The liver is the second most common organ for metastasis and liver metastasis is one of the leading causes of cancer-related mortality. There are currently no reliable biomarkers that impact clinical management in patients with liver metastases.
van Dam, Pieter-Jan
core   +3 more sources

High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern

Molecular Therapy: Oncology
To date, nearly one-quarter of colorectal cancer (CRC) patients develop liver metastases (CRCLM), and its aggressiveness can be correlated to defined histopathological growth patterns (HGP).
Shuang Fan, Johannes Robert Fleischer, Lolita Dokshokova, Lena Sophie Böhme, Gwendolyn Haas, Alexandra Maria Schmitt, Fabio Bennet Gätje, Linde-Allegra Emmalie Rosen, Hanibal Bohnenberger, Michael Ghadimi, Baolong Cui, Xingbo Xu, Joanna Maria Kalucka, Florian Bösch, Tiago De Oliveira, Lena-Christin Conradi   +15 more
doaj   +3 more sources

Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights. [PDF]

Br J Cancer, 2022
The first consensus guidelines for scoring the histopathological growth patterns (HGPs) of liver metastases were established in 2017. Since then, numerous studies have applied these guidelines, have further substantiated the potential clinical value of the HGPs in patients with liver metastases from various tumour types and are starting to shed light ...
Latacz E, Höppener D, Bohlok A, Leduc S, Tabariès S, Fernández Moro C, Lugassy C, Nyström H, Bozóky B, Floris G, Geyer N, Brodt P, Llado L, Van Mileghem L, De Schepper M, Majeed AW, Lazaris A, Dirix P, Zhang Q, Petrillo SK, Vankerckhove S, Joye I, Meyer Y, Gregorieff A, Roig NR, Vidal-Vanaclocha F, Denis L, Oliveira RC, Metrakos P, Grünhagen DJ, Nagtegaal ID, Mollevi DG, Jarnagin WR, D'Angelica MI, Reynolds AR, Doukas M, Desmedt C, Dirix L, Donckier V, Siegel PM, Barnhill R, Gerling M, Verhoef C, Vermeulen PB.   +43 more
europepmc   +6 more sources

Differentiation of histopathological growth patterns of colorectal liver metastases by MRI features. [PDF]

Quant Imaging Med Surg, 2022
It is necessary to develop an accurate non-invasive method to determine the histopathological growth pattern (HGP) of colorectal liver metastasis (CRLM) before surgery. The present study aimed to identify various HGPs of CRLM by magnetic resonance imaging (MRI) features.This retrospective study included 53 chemo-naïve patients with CRLM between ...
Li WH, Wang S, Liu Y, Wang XF, Wang YF, Chai RM.   +5 more
europepmc   +4 more sources