Results 31 to 40 of about 8,202,239 (241)

International consensus guidelines for scoring the histopathological growth patterns of liver metastasis. [PDF]

Br J Cancer, 2017
Liver metastases present with distinct histopathological growth patterns (HGPs), including the desmoplastic, pushing and replacement HGPs and two rarer HGPs. The HGPs are defined owing to the distinct interface between the cancer cells and the adjacent normal liver parenchyma that is present in each pattern and can be scored from standard haematoxylin ...
van Dam PJ, van der Stok EP, Teuwen LA, Van den Eynden GG, Illemann M, Frentzas S, Majeed AW, Eefsen RL, Coebergh van den Braak RRJ, Lazaris A, Fernandez MC, Galjart B, Laerum OD, Rayes R, Grünhagen DJ, Van de Paer M, Sucaet Y, Mudhar HS, Schvimer M, Nyström H, Kockx M, Bird NC, Vidal-Vanaclocha F, Metrakos P, Simoneau E, Verhoef C, Dirix LY, Van Laere S, Gao ZH, Brodt P, Reynolds AR, Vermeulen PB.   +31 more
europepmc   +8 more sources

Histopathological growth patterns and positive margins after resection of colorectal liver metastases. [PDF]

HPB (Oxford), 2020
Histopathological growth patterns (HGPs) of colorectal liver metastases (CRLM) may be an expression of biological tumour behaviour impacting the risk of positive resection margins. The current study aimed to investigate whether the non-desmoplastic growth pattern (non-dHGP) is associated with a higher risk of positive resection margins after resection ...
Nierop PMH, Höppener DJ, van der Stok EP, Galjart B, Buisman FE, Balachandran VP, Jarnagin WR, Kingham TP, Allen PJ, Shia J, Vermeulen PB, Groot Koerkamp B, Grünhagen DJ, Verhoef C, D'Angelica MI.   +14 more
europepmc   +4 more sources

The intraoral growth patterns of parapharyngeal tumors: A proposed classification system

Ear, Nose & Throat Journal, 2023
Objective: Nearly half of parapharyngeal space (PPS) tumors present as an intraoral mass, which is diagnostically challenging. In this study, we studied whether preoperative growth patterns were associated with histopathological diagnosis for planning ...
Yanjun Feng MD, Jianhong Wang MD, Xiping Li MD, Lingzhao Meng MD, Yuansheng Rao MD, Fan Yang MD   +5 more
doaj   +1 more source

Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution

Molecular Cancer, 2023
Background Colorectal cancer liver metastases (CRCLM) are associated with a poor prognosis, reflected by a five-year survival rate of 14%. Anti-angiogenic therapy through anti-VEGF antibody administration is one of the limited therapies available ...
Johannes Robert Fleischer, Alexandra Maria Schmitt, Gwendolyn Haas, Xingbo Xu, Elisabeth Maria Zeisberg, Hanibal Bohnenberger, Stefan Küffer, Laure-Anne Teuwen, Philipp Johannes Karras, Tim Beißbarth, Annalen Bleckmann, Mélanie Planque, Sarah-Maria Fendt, Peter Vermeulen, Michael Ghadimi, Joanna Kalucka, Tiago De Oliveira, Lena-Christin Conradi   +17 more
doaj   +1 more source

Histopathological Study of the Prostate Cancer Growth Patterns in Relation with the Grading Systems.

Current health sciences journal, 2022
Prostate adenocarcinomas are common lesions with a high incidence and variable prognosis, which can be assessed using tumor grading systems. In this study, we analyzed 329 prostate adenocarcinomas in relation to tumor variants, growth patterns, classical and updated grading systems.
Popescu, Tudor Cristian Timotei, Stepan, Alex Emilian, Florescu, Mirela Marinela, Simionescu, Cristiana Eugenia   +3 more
openaire   +2 more sources

Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice. [PDF]

PLoS ONE, 2016
Previously, we generated a preclinical mouse prostate tumor model based on PSA-Cre driven inactivation of Pten. In this model homogeneous hyperplastic prostates (4-5m) developed at older age (>10m) into tumors.
Hanneke Korsten, Angelique C J Ziel-van der Made, Wytske M van Weerden, Theo van der Kwast, Jan Trapman, Petra W Van Duijn   +5 more
doaj   +1 more source

Noninvasive molecular imaging signatures of histopathological growth patterns in colorectal cancer liver metastases. [PDF]

Clin Exp Metastasis
Colorectal cancer liver metastases (CRLM) are characterized by distinct histopathological growth patterns (HGPs), desmoplastic (dHGP) also called encapsulated, replacement (rHGP) and pushing (pHGP) types, which have major prognostic and therapeutic implications. HGPs can only be determined histologically after surgical resection.
Vierasu I, Sclafani F, Van Laethem JL, Delbart W, Doumont G, Bohlok A, Donckier V, Flamen P.   +7 more
europepmc   +4 more sources

tumour-growth-patterns-impact-evolution

, 2021
Agent-based modelling reveals the impact of growth patterns on spatial and temporal features of clonal diversification.
Yue Zhao (8126637), Kevin Litchfield (7557590), Samra Turajlic (7561664), Xiao Fu (7558586), Paul Bates (7556462), Erik Sahai (7559030)   +5 more
core   +1 more source

Spatial analysis of histology in 3D: quantification and visualization of organ and tumor level tissue environment

Heliyon, 2022
Histological changes in tissue are of primary importance in pathological research and diagnosis. Automated histological analysis requires ability to computationally separate pathological alterations from normal tissue.
Pekka Ruusuvuori, Masi Valkonen, Kimmo Kartasalo, Mira Valkonen, Tapio Visakorpi, Matti Nykter, Leena Latonen   +6 more
doaj   +1 more source

Histopathological growth pattern and vessel co-option in intrahepatic cholangiocarcinoma

Medical Molecular Morphology
AbstractIntrahepatic cholangiocarcinoma (iCCA) exhibits different blood imaging features and prognosis depending on histology. To clarity histopathological growth patterns (HGPs) and vascularization processes of iCCA, we collected 145 surgical specimens and histologically classified them into large bile duct (LBD) (20 cases), small bile duct (SBD) (54),
Zihan Li, Hiep Nguyen Canh, Kenta Takahashi, Dong Le Thanh, Quynh Nguyen Thi, Rui Yang, Kaori Yoshimura, Yasunori Sato, Khuyen Nguyen Thi, Hiroki Nakata, Hiroko Ikeda, Kazuto Kozaka, Satoshi Kobayashi, Shintaro Yagi, Kenichi Harada   +14 more
  +7 more sources