Results 101 to 110 of about 194,482 (300)

Cultural-Historical Psychology and Activity Approach in Education” Research Master’s Program: Testing the New Modules at the Volgograd State Socio-Pedagogical University

, 2015
We analyzed experience in testing new modules of basic professional educational program for “Cultural-historical psychology and activity approach in education” research master’s course at the Volgograd State Socio-Pedagogical University.
Kritsky A. G.,, Andruschenko T. Ju, Merkulova O. P.   +2 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Cultural Dimension of the Communist Party in Manzanillo (1925-1935)

Santiago, 2015
The present research work, a partial result of a scientific project, allows an approach to the activity of  Manzanillo  communists during  the stage from 1925 to 1935.
MSc. Aida Mercedes Sera-Fernández
doaj  

Joint waking activity in early childhood education as a collaborative configuration of care

Although sleeping and waking are everyday activities and inherent parts of being human, they are rarely considered social, collaborative, or educational. In this study, we explore practices of waking young children up in institutional interaction. Taking
Pursi, Annukka, Cekaite, Asta, Lipponen, Lasse, Cekaite, Asta,, Pursi, Annukka,, Lipponen, Lasse,   +5 more
core   +1 more source

Cultural Historical Activity Theory and Student Writing [PDF]

, 2013
Writing, often in conjunction with other media, is profoundly important to higher education, as it is to other modern institutions students will enter. Student writing mediates much of the activity of learning, and the most crucial parts, typically, such
Russell, David
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

THE PEDAGOGICAL EFFECTIVENESS OF THE HISTORICAL AND CULTURAL APPROACH IN FRENCH LANGUAGE EDUCATION

This article examines the pedagogical potential and educational effectiveness of applying a historical and cultural approach to French language teaching. It argues that learning a foreign language involves more than acquiring grammatical rules, vocabulary, and speech skills; learners also need to understand the history, culture, values, social life ...
Xolbekova Sayyoraxon Amanjanovna, Salaydinov Ma'rufjon Maxamadjonovich   +1 more
openaire   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

The cultural-historical approach as the basis of a methodology for strategic learning of writing in a foreign language

Revista MENDIVE, 2007
The historical-cultural approach is one of the most influential psychological theories nowadays. Foreign language teaching-learning has not been away from this influence.
Vilma María Pérez Viñas
doaj